TECR, trans-2,3-enoyl-CoA reductase

TECR, trans-2,3-enoyl-CoA reductase

• This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011]

• Gene Synonyms (very-long-chain enoyl-CoA reductase, epididymis secretory sperm binding protein, glycoprotein, synaptic 2, synaptic glycoprotein SC2, GPSN2, MRT14, SC2, TER,)
• NCBI Gene ID: 9524
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NZ01
  UNIPROT ID#>>B3KSQ1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

trans-2,3-enoyl-CoA reductase interacts with:

• 3-hydroxyacyl-CoA dehydratase 2
  ADP ribosylation factor like GTPase 13B
  aurora kinase A interacting protein 1
  autophagy and beclin 1 regulator 1
  autophagy related 16 like 1
  Bet1 golgi vesicular membrane trafficking protein
  cAMP responsive element binding protein 3
  cAMP responsive element binding protein 3 like 1
  CCCTC-binding factor
  CDGSH iron sulfur domain 1
  ceramide synthase 2
  clusterin associated protein 1
  crumbs cell polarity complex component 3
  cullin 7
  cullin associated and neddylation dissociated 1
  egl-9 family hypoxia inducible factor 3
  EH domain containing 1
  ELOVL fatty acid elongase 1
  ERGIC and golgi 3
  family with sequence similarity 209 member A
  F-box protein 7
  golgi reassembly stacking protein 2
  golgi transport 1A
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  homeodomain interacting protein kinase 4
  hydroxysteroid 17-beta dehydrogenase 12
  integrin alpha FG-GAP repeat containing 1
  interferon induced transmembrane protein 3
  jagunal homolog 1
  kinase suppressor of ras 1
  limb development membrane protein 1 like
  magnesium transporter 1
  major facilitator superfamily domain containing 14B
  membrane bound O-acyltransferase domain containing 1
  membrane magnesium transporter 1
  mitotic arrest deficient 2 like 2
  PAX interacting protein 1
  pleckstrin homology domain containing A4
  PR/SET domain 16
  progesterone receptor membrane component 2
  pyrin and HIN domain family member 1
  RAB1B, member RAS oncogene family
  ras homolog family member T2
  receptor interacting serine/threonine kinase 4
  reticulophagy regulator family member 3
  ring finger and CCCH-type domains 2
  ring finger protein 157
  SEC61 translocon subunit alpha 1
  secretory carrier membrane protein 3
  slingshot protein phosphatase 1
  solute carrier family 10 member 6
  solute carrier family 15 member 3
  solute carrier family 7 member 14
  stimulator of interferon response cGAMP interactor 1
  tectonic family member 2
  TNFAIP3 interacting protein 2
  trans-golgi network protein 2
  translocase of outer mitochondrial membrane 22
  unc-93 homolog B1, TLR signaling regulator
  vacuolar ATPase assembly factor VMA21
  vir like m6A methyltransferase associated
  WW domain containing oxidoreductase
  zinc finger CCCH-type containing 7A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.