TCTN2, tectonic family member 2

TCTN2, tectonic family member 2

• This gene encodes a type I membrane protein that belongs to the tectonic family. Studies in mice suggest that this protein may be involved in hedgehog signaling, and essential for ciliogenesis. Mutations in this gene are associated with Meckel syndrome type 8. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

• Gene Synonyms (tectonic-2, C12orf38, JBTS24, MKS8, TECT2,)
• NCBI Gene ID: 79867
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96GX1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tectonic family member 2 interacts with:

• 3-hydroxyacyl-CoA dehydratase 2
  anoctamin 6
  B9 domain containing 2
  BRI3 binding protein
  butyrophilin like 8
  CDGSH iron sulfur domain 2
  charged multivesicular body protein 7
  chromosome 18 open reading frame 32
  CLPTM1 like
  coiled-coil domain containing 115
  dihydrofolate reductase 2
  discoidin, CUB and LCCL domain containing 2
  divergent protein kinase domain 1B
  ER membrane protein complex subunit 10
  ER membrane protein complex subunit 6
  G protein-coupled receptor 89A
  galactosidase beta 1 like 2
  glycerol-3-phosphate acyltransferase 3
  glycerol-3-phosphate acyltransferase 4
  histocompatibility minor 13
  IKBKB interacting protein
  inositol 1,4,5-trisphosphate receptor interacting protein
  jagunal homolog 1
  jumonji domain containing 8
  keratinocyte associated protein 2
  LARGE xylosyl- and glucuronyltransferase 2
  lipase maturation factor 2
  lunapark, ER junction formation factor
  LY6/PLAUR domain containing 6
  magnesium transporter 1
  membrane bound O-acyltransferase domain containing 2
  membrane magnesium transporter 1
  neurexophilin and PC-esterase domain family member 3
  NUS1 dehydrodolichyl diphosphate synthase subunit
  oxysterol binding protein like 8
  phosphatidylinositol glycan anchor biosynthesis class S
  phosphatidylinositol glycan anchor biosynthesis class U
  post-GPI attachment to proteins inositol deacylase 1
  RAB, member of RAS oncogene family like 3
  RFT1 homolog
  SEC11 homolog C, signal peptidase complex subunit
  sorting nexin 19
  stearoyl-CoA desaturase 5
  STT3 oligosaccharyltransferase complex catalytic subunit B
  synaptosome associated protein 47
  TAFA chemokine like family member 4
  thioredoxin related transmembrane protein 1
  TLC domain containing 1
  TLC domain containing 2
  transmembrane protein 120B
  transmembrane protein 199
  transmembrane protein 209
  transmembrane protein 219
  transmembrane protein 222
  transmembrane protein 35B
  transmembrane protein 67
  vacuolar ATPase assembly factor VMA21
  vacuole membrane protein 1
  vitamin K epoxide reductase complex subunit 1 like 1
  Wnt ligand secretion mediator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.