MAD2L2, mitotic arrest deficient 2 like 2

MAD2L2, mitotic arrest deficient 2 like 2

• The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008]

• Gene Synonyms (FANCV, MAD2B, POLZ2, REV7, mitotic spindle assembly checkpoint protein MAD2B, MAD2 (mitotic arrest deficient, yeast, homolog)-like 2, MAD2 mitotic arrest deficient-like 2, MAD2-like protein 2, REV7 homolog, hREV7, mitotic arrest deficient 2-like protein 2, mitotic arrest deficient homolog-like 2, polymerase (DNA-directed), zeta 2, accessory subunit,)
• NCBI Gene ID: 10459
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R4I4
  UNIPROT ID#>>Q9UI95
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitotic arrest deficient 2 like 2 interacts with:

• abhydrolase domain containing 12, lysophospholipase
  AFG3 like matrix AAA peptidase subunit 2
  ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase
  ATP synthase membrane subunit DAPIT
  bridging integrator 3
  calcineurin like EF-hand protein 1
  carbohydrate sulfotransferase 12
  catechol-O-methyltransferase domain containing 1
  CDC42 effector protein 1
  CDC42 small effector 2
  cell cycle and apoptosis regulator 2
  chromobox 1
  chromobox 1
  chromobox 3
  chromobox 5
  chromosome 20 open reading frame 85
  chromosome alignment maintaining phosphoprotein 1
  CLN6 transmembrane ER protein
  Coenzyme A synthase
  cytochrome c oxidase assembly factor 3
  cytochrome c oxidase assembly factor COX20
  dephospho-CoA kinase domain containing
  dicer 1, ribonuclease III
  DNA polymerase delta 3, accessory subunit
  DNA polymerase delta interacting protein 2
  DnaJ heat shock protein family (Hsp40) member C19
  DTW domain containing 1
  DTW domain containing 2
  dynactin subunit 3
  dynamin binding protein
  extended synaptotagmin 2
  family with sequence similarity 174 member A
  family with sequence similarity 217 member B
  family with sequence similarity 78 member B
  fatty acyl-CoA reductase 1
  fizzy and cell division cycle 20 related 1
  FTO alpha-ketoglutarate dependent dioxygenase
  glutaminyl-peptide cyclotransferase like
  glutathione peroxidase 8 (putative)
  HEPACAM family member 2
  HIG1 hypoxia inducible domain family member 1A
  IKAROS family zinc finger 3
  inhibitor of CDK, cyclin A1 interacting protein 1
  LEM domain containing 3
  leucine rich repeat and fibronectin type III domain containing 4
  lysosomal associated membrane protein 3
  MAD2 mitotic arrest deficient-like 2
  matrix AAA peptidase interacting protein 1
  methyl-CpG binding domain protein 3 like 1
  mitochondrial E3 ubiquitin protein ligase 1
  mitochondrial ribosomal protein L17
  mitotic arrest deficient 2 like 2
  MLLT11 transcription factor 7 cofactor
  N-acetyltransferase 14 (putative)
  NADH:ubiquinone oxidoreductase complex assembly factor 4
  neuroplastin
  NFKB inhibitor interacting Ras like 2
  nicastrin
  nuclear RNA export factor 1
  nucleoside-triphosphatase, cancer-related
  OCIA domain containing 1
  OTU deubiquitinase 5
  pleckstrin homology like domain family A member 1
  PNKD metallo-beta-lactamase domain containing
  pogo transposable element derived with ZNF domain
  potassium channel tetramerization domain containing 9
  progesterone receptor membrane component 1
  proline rich 12
  proline rich 5 like
  prostaglandin E synthase 2
  protein phosphatase 1 regulatory subunit 13 like
  quiescin sulfhydryl oxidase 2
  RAB11 family interacting protein 4
  RAB34, member RAS oncogene family
  ras homolog family member F, filopodia associated
  ras homolog family member T2
  REV1 DNA directed polymerase
  REV1, DNA directed polymerase
  ribonuclease P/MRP subunit p30
  ribosomal protein L22 like 1
  ribosomal protein S27 like
  serine peptidase inhibitor, Kunitz type 2
  shieldin complex subunit 1
  shieldin complex subunit 2
  sideroflexin 3
  solute carrier family 25 member 22
  solute carrier family 27 member 2
  solute carrier family 7 member 11
  sperm acrosome associated 1
  SRP receptor subunit beta
  stromal cell derived factor 4
  synapse defective Rho GTPase homolog 1
  THAP domain containing 6
  translocase of inner mitochondrial membrane 21
  transmembrane protein 9
  tripartite motif containing 54
  tripartite motif containing 7
  TSPY like 6
  vesicle transport through interaction with t-SNAREs 1B
  WW domain binding protein 2
  yippee like 3
  YME1 like 1 ATPase
  YY1 associated protein 1
  zinc finger MYND-type containing 12
  zinc finger protein 281
  zinc finger protein 511
  zinc finger protein 558
  zinc finger protein 655
  zinc finger RNA binding protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.