CLN6, CLN6 transmembrane ER protein

CLN6, CLN6 transmembrane ER protein

• This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008]

• Gene Synonyms (ceroid-lipofuscinosis neuronal protein 6, ceroid-lipofuscinosis neuronal 6 late infantile, ceroid-lipofuscinosis, neuronal 6, late infantile, CLN4A, HsT18960, nclf,)
• NCBI Gene ID: 54982
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R601
  UNIPROT ID#>>Q9NWW5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CLN6 transmembrane ER protein interacts with:

• ADP ribosylation factor like GTPase 13B
  cAMP responsive element binding protein 3 like 1
  CDGSH iron sulfur domain 2
  complexin 4
  cytochrome b-245 chaperone 1
  derlin 1
  egl-9 family hypoxia inducible factor 3
  family with sequence similarity 209 member A
  fibronectin type III domain containing 9
  golgin, RAB6 interacting
  leucine rich repeat containing 25
  RIC3 acetylcholine receptor chaperone
  solute carrier family 22 member 23
  transmembrane protein 139
  transmembrane protein 237

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.