RIC3, RIC3 acetylcholine receptor chaperone

RIC3, RIC3 acetylcholine receptor chaperone

• This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

• Gene Synonyms (protein RIC-3, resistance to inhibitors of cholinesterase 3-like protein, resistant to inhibitor of cholinesterase 3, AYST720, PRO1385,)
• NCBI Gene ID: 79608
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7Z5B4
  UNIPROT ID#>>B7Z3Z0
  UNIPROT ID#>>D3DQU6
  UNIPROT ID#>>A0A0S2Z607
  UNIPROT ID#>>A0A0S2Z6D3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RIC3 acetylcholine receptor chaperone interacts with:

• chromosome 6 open reading frame 120
  fetal and adult testis expressed 1
  phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
  solute carrier family 30 member 7
  TRAF3 interacting protein 3
  transmembrane and ubiquitin like domain containing 1
  transmembrane anterior posterior transformation 1
  transmembrane protein 86A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.