SEC61A1, SEC61 translocon subunit alpha 1

SEC61A1, SEC61 translocon subunit alpha 1

• The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]

• Gene Synonyms (protein transport protein Sec61 subunit alpha isoform 1, SEC61 translocon alpha 1 subunit, Sec61 alpha 1 subunit, Sec61 alpha-1, protein transport protein SEC61 alpha subunit, protein transport protein Sec61 subunit alpha, sec61 homolog, HNFJ4, HSEC61, SEC61, SEC61A,)
• NCBI Gene ID: 29927
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P61619
  UNIPROT ID#>>B3KME8
  UNIPROT ID#>>B3KNF6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SEC61 translocon subunit alpha 1 interacts with:

• centrosomal protein 152
  cyclic GMP-AMP synthase
  derlin 1
  derlin 2
  derlin 3
  dynactin 3
  integrin alpha FG-GAP repeat containing 1
  jagunal homolog 1
  leucine rich repeat protein 1
  limb development membrane protein 1 like
  MAD2 mitotic arrest deficient-like 1
  magnesium transporter 1
  nucleoporin 107
  O-sialoglycoprotein endopeptidase
  pleckstrin homology domain containing A4
  polycomb group ring finger 1
  protein tyrosine phosphatase non-receptor type 5
  ring finger and CCCH-type domains 2
  SEC61 translocon subunit alpha 1
  stimulator of interferon response cGAMP interactor 1
  synoviolin 1
  transmembrane protein 41B
  UFM1 specific ligase 1
  UPF3B regulator of nonsense mediated mRNA decay
  WW domain containing oxidoreductase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.