TGOLN2, trans-golgi network protein 2

TGOLN2, trans-golgi network protein 2

• This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

• Gene Synonyms (TGN38, TGN46, TGN48, TGN51, TTGN2, hTGN46, hTGN48, hTGN51, trans-Golgi network integral membrane protein 2, TGN38 homolog, trans-Golgi network glycoprotein 46, trans-Golgi network glycoprotein 48, trans-Golgi network glycoprotein 51, trans-Golgi network protein (46, 48, 51kD isoforms), trans-Golgi network protein TGN51,)
• NCBI Gene ID: 10618
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43493
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

trans-golgi network protein 2 interacts with:

• 3-hydroxyacyl-CoA dehydratase 3
  acyl-CoA binding domain containing 3
  adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
  adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
  adaptor related protein complex 1 associated regulatory protein
  adaptor related protein complex 3 subunit mu 1
  adaptor related protein complex 4 subunit epsilon 1
  adaptor related protein complex 4 subunit sigma 1
  adenosylhomocysteinase like 1
  adenosylhomocysteinase like 2
  ADP ribosylation factor GTPase activating protein 2
  ADP ribosylation factor GTPase activating protein 3
  ADP ribosylation factor interacting protein 1
  ADP ribosylation factor like GTPase 13B
  ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase
  ALG2 alpha-1,3/1,6-mannosyltransferase
  ankyrin repeat domain 27
  ATPase 13A3
  ATPase family AAA domain containing 3B
  ATPase H+ transporting V1 subunit D
  ATPase secretory pathway Ca2+ transporting 1
  Bet1 golgi vesicular membrane trafficking protein like
  BLOC-1 related complex subunit 6
  BMP2 inducible kinase
  BRCA2 and CDKN1A interacting protein
  C9orf72-SMCR8 complex subunit
  cell division cycle associated 3
  COPI coat complex subunit epsilon
  COPI coat complex subunit gamma 1
  COPI coat complex subunit gamma 2
  copine 8
  cytoplasmic FMR1 interacting protein 1
  cytoplasmic FMR1 interacting protein 2
  cytoskeleton associated protein 4
  DEAD-box helicase 54
  DEAD-box helicase 56
  dedicator of cytokinesis 5
  DENN domain containing 11
  DENN domain containing 4C
  DENN domain containing 6A
  DEP domain containing 1B
  DExH-box helicase 30
  DNA polymerase delta interacting protein 3
  EH domain binding protein 1
  epidermal growth factor receptor pathway substrate 15 like 1
  epsin 1
  epsin 2
  ER degradation enhancing alpha-mannosidase like protein 3
  exportin for tRNA
  extended synaptotagmin 1
  FA complementation group I
  family with sequence similarity 135 member A
  family with sequence similarity 219 member A
  family with sequence similarity 234 member B
  family with sequence similarity 83 member B
  family with sequence similarity 91 member A1
  FCH and mu domain containing endocytic adaptor 2
  fermitin family member 2
  FtsJ RNA 2'-O-methyltransferase 3
  G protein nucleolar 3
  G protein nucleolar 3 like
  glycerol-3-phosphate dehydrogenase 1 like
  golgi associated PDZ and coiled-coil motif containing
  golgi associated, gamma adaptin ear containing, ARF binding protein 1
  golgi associated, gamma adaptin ear containing, ARF binding protein 3
  golgi phosphoprotein 3
  golgi reassembly stacking protein 2
  golgin, RAB6 interacting
  GPN-loop GTPase 3
  GRIP and coiled-coil domain containing 1
  GRIP1 associated protein 1
  GTP binding protein 4
  GTPase activating protein and VPS9 domains 1
  HEAT repeat containing 1
  heat shock protein family A (Hsp70) member 12A
  heterochromatin protein 1 binding protein 3
  histocompatibility minor 13
  hook microtubule tethering protein 3
  ilvB acetolactate synthase like
  inner membrane mitochondrial protein
  integrator complex subunit 1
  integrator complex subunit 12
  integrator complex subunit 2
  integrator complex subunit 4
  integrator complex subunit 5
  intersectin 2
  keratin associated protein 10-9
  KIAA0319 like
  kinase D interacting substrate 220
  kinesin family member 16B
  kinesin light chain 4
  KRI1 homolog
  late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
  LEM domain containing 3
  leucine rich repeat kinase 2
  leucyl-tRNA synthetase 2, mitochondrial
  lin-7 homolog C, crumbs cell polarity complex component
  lipolysis stimulated lipoprotein receptor
  listerin E3 ubiquitin protein ligase 1
  Ly1 antibody reactive
  Mab-21 domain containing 2
  MARCKS like 1
  membrane palmitoylated protein 7
  midasin AAA ATPase 1
  mitochondrial ribosomal protein L11
  mitochondrial ribosomal protein L37
  mitochondrial ribosomal protein S35
  MON2 homolog, regulator of endosome-to-Golgi trafficking
  N-acetyltransferase 10
  neurobeachin
  niban apoptosis regulator 2
  nischarin
  NOP16 nucleolar protein
  NOP2/Sun RNA methyltransferase 2
  NOP53 ribosome biogenesis factor
  nuclear receptor coactivator 7
  nucleoporin 188
  nucleoporin 205
  nucleoporin 85
  nucleoside-triphosphatase, cancer-related
  nudix hydrolase 19
  occludin
  oxysterol binding protein like 10
  oxysterol binding protein like 11
  oxysterol binding protein like 9
  PDS5 cohesin associated factor B
  PGAM family member 5, mitochondrial serine/threonine protein phosphatase
  phosphoinositide kinase, FYVE-type zinc finger containing
  phosphoinositide-3-kinase regulatory subunit 4
  pleckstrin homology domain containing A1
  progesterone receptor membrane component 1
  protein kinase C and casein kinase substrate in neurons 2
  protein kinase D2
  protein phosphatase 1 regulatory subunit 21
  protein phosphatase 1 regulatory subunit 37
  protein phosphatase 1 regulatory subunit 9A
  protein phosphatase 1 regulatory subunit 9B
  protein tyrosine phosphatase non-receptor type 23
  pseudopodium enriched atypical kinase 1
  pyridoxal dependent decarboxylase domain containing 1
  RAB, member of RAS oncogene family like 3
  RAB, member RAS oncogene family like 6
  RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
  RAB14, member RAS oncogene family
  RAB18, member RAS oncogene family
  RAB21, member RAS oncogene family
  rabenosyn, RAB effector
  Ral GTPase activating protein non-catalytic subunit beta
  RELT like 1
  rhomboid domain containing 3
  ribosomal protein S6 kinase C1
  ribosomal RNA processing 12 homolog
  ribosomal RNA processing 1B
  RIC1 homolog, RAB6A GEF complex partner 1
  RNA binding motif protein 28
  RNA binding motif protein 33
  RNA binding motif protein 34
  RUN and FYVE domain containing 1
  RUS family member 1
  scribble planar cell polarity protein
  SCY1 like pseudokinase 2
  SCY1 like pseudokinase 3
  sec1 family domain containing 1
  SEC23 interacting protein
  SEC24 homolog A, COPII coat complex component
  SEC61 translocon subunit alpha 1
  secretion associated Ras related GTPase 1A
  semaphorin 4C
  shisa family member 2
  small ArfGAP2
  SMCR8-C9orf72 complex subunit
  SNAP associated protein
  solute carrier family 12 member 7
  solute carrier family 30 member 5
  solute carrier family 30 member 6
  solute carrier family 38 member 1
  solute carrier family 38 member 2
  solute carrier family 39 member 10
  solute carrier family 39 member 14
  solute carrier family 6 member 15
  sorting nexin 27
  sorting nexin 29
  sorting nexin 5
  sorting nexin 6
  sorting nexin family member 30
  sprouty RTK signaling antagonist 4
  SRP receptor subunit beta
  STEAP3 metalloreductase
  stonin 2
  STT3 oligosaccharyltransferase complex catalytic subunit B
  synapse associated protein 1
  synergin gamma
  syntaxin 12
  TBC1 domain family member 22A
  TBC1 domain family member 22B
  TBC1 domain family member 23
  tight junction associated protein 1
  torsin 1A interacting protein 1
  trafficking protein particle complex 1
  trafficking protein particle complex 11
  trafficking protein particle complex 12
  trafficking protein particle complex 13
  trafficking protein particle complex 2 like
  trafficking protein particle complex 3
  trafficking protein particle complex 4
  trafficking protein particle complex 5
  trafficking protein particle complex 6B
  trafficking protein particle complex 8
  trafficking protein particle complex 9
  trans-golgi network protein 2
  transmembrane protein 106B
  transmembrane protein 230
  transmembrane protein 87A
  UbiA prenyltransferase domain containing 1
  ubiquitin protein ligase E3 component n-recognin 4
  ubiquitin specific peptidase 32
  UHRF1 binding protein 1
  UHRF1 binding protein 1 like
  unc-5 netrin receptor B
  vacuolar protein sorting 13 homolog B
  vacuolar protein sorting 45 homolog
  VANGL planar cell polarity protein 1
  vezatin, adherens junctions transmembrane protein
  VPS16 core subunit of CORVET and HOPS complexes
  VPS18 core subunit of CORVET and HOPS complexes
  VPS33A core subunit of CORVET and HOPS complexes
  VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
  VPS33B late endosome and lysosome associated
  VPS54 subunit of GARP complex
  VPS8 subunit of CORVET complex
  WASH complex subunit 2A
  WASH complex subunit 2C
  WASH complex subunit 3
  WASH complex subunit 4
  WD repeat domain 11
  WD repeat domain 20
  WD repeat domain 41
  WD repeat domain 6
  WD repeat domain 7
  WW domain containing oxidoreductase
  YKT6 v-SNARE homolog
  YTH N6-methyladenosine RNA binding protein 3
  zinc finger CCCH-type containing, antiviral 1
  zinc finger DHHC-type palmitoyltransferase 20
  zinc finger protein 512

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.