RAB14, RAB14, member RAS oncogene family

RAB14, RAB14, member RAS oncogene family

• RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009]

• Gene Synonyms (ras-related protein Rab-14, F protein-binding protein 1, bA165P4.3 (member RAS oncogene family), small GTP binding protein RAB14, FBP, RAB-14,)
• NCBI Gene ID: 51552
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R845
  UNIPROT ID#>>P61106
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RAB14, member RAS oncogene family interacts with:

• centrosomal protein 43
  coiled-coil domain containing 8
  dual specificity phosphatase 22
  family with sequence similarity 71 member C
  filamin, beta
  folliculin
  limb development membrane protein 1 like
  NHL repeat containing 2
  PIH1 domain containing 1
  potassium channel tetramerization domain containing 12
  RAB11 family interacting protein 1
  RAB2B, member RAS oncogene family
  RAB4B, member RAS oncogene family
  rabenosyn, RAB effector
  ring finger and FYVE like domain containing E3 ubiquitin protein ligase
  RUN and FYVE domain containing 1
  SH3 binding domain protein 5 like
  SMAD specific E3 ubiquitin protein ligase 2
  solute carrier family 25 member 41
  testis expressed 101
  unk zinc finger

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.