STEAP3, STEAP3 metalloreductase

STEAP3, STEAP3 metalloreductase

• This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

• Gene Synonyms (AHMIO2, STMP3, TSAP6, dudlin-2, dudulin-2, pHyde, metalloreductase STEAP3, STEAP family member 3, metalloreductase, six-transmembrane epithelial antigen of prostate 3, tumor suppressor pHyde, tumor suppressor-activated pathway protein 6,)
• NCBI Gene ID: 55240
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q658P3
  UNIPROT ID#>>B8ZZX6
  UNIPROT ID#>>A0A024RAD7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

STEAP3 metalloreductase interacts with:

• ectonucleotide pyrophosphatase/phosphodiesterase 6
  family with sequence similarity 177 member A1
  melanocortin 2 receptor accessory protein 2
  metadherin
  metallo-beta-lactamase domain containing 2
  pleckstrin homology domain containing A4
  SET domain containing 7, histone lysine methyltransferase
  sodium voltage-gated channel beta subunit 3
  solute carrier family 39 member 4
  sorting nexin 27
  testis expressed 29
  tetratricopeptide repeat domain 21A
  tigger transposable element derived 5
  transmembrane protein 17

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.