MRAP2, melanocortin 2 receptor accessory protein 2

MRAP2, melanocortin 2 receptor accessory protein 2

• This gene encodes a protein that modulates melanocortin receptor signaling. The encoded protein has been shown to interact with all known melanocortin receptors and may regulate both receptor trafficking and activation in response to ligands. Mice lacking a functional copy of this gene exhibit severe obesity and a mutation in this gene may be associated with severe obesity in human patients. [provided by RefSeq, Oct 2016]

• Gene Synonyms (C6orf117, bA51G5.2, melanocortin-2 receptor accessory protein 2, MC2R accessory protein 2,)
• NCBI Gene ID: 112609
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96G30
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

melanocortin 2 receptor accessory protein 2 interacts with:

• pecanex 3
  ring finger protein 149
  transmembrane protein 80

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.