PDS5B, PDS5 cohesin associated factor B

PDS5B, PDS5 cohesin associated factor B

• This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. [provided by RefSeq, Jul 2015]

• Gene Synonyms (APRIN, AS3, CG008, sister chromatid cohesion protein PDS5 homolog B, androgen induced inhibitor of proliferation, androgen-induced proliferation inhibitor, androgen-induced prostate proliferative shutoff-associated protein AS3, androgen-induced shutoff 3,)
• NCBI Gene ID: 23047
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NTI5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PDS5 cohesin associated factor B interacts with:

• CD274 molecule
  cell division cycle associated 5
  cell division cycle associated 5
  clusterin associated protein 1
  family with sequence similarity 234 member B
  histone H3 associated protein kinase
  limb development membrane protein 1 like
  LY6/PLAUR domain containing 3
  MIS12 kinetochore complex component
  NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
  obscurin like cytoskeletal adaptor 1
  partner and localizer of BRCA2
  PDS5 cohesin associated factor A
  pleckstrin homology domain containing A4
  septin 12
  sirtuin 7
  sodium voltage-gated channel beta subunit 3
  structural maintenance of chromosomes 1A
  TNFAIP3 interacting protein 2
  vir like m6A methyltransferase associated
  WAP four-disulfide core domain 5
  WAPL cohesin release factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.