GGA1, golgi associated, gamma adaptin ear containing, ARF binding protein 1

GGA1, golgi associated, gamma adaptin ear containing, ARF binding protein 1

• This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ADP-ribosylation factor-binding protein GGA1, ADP-ribosylation factor binding protein 1, gamma-adaptin related protein 1, golgi-localized, gamma ear-containing, ARF-binding protein 1,)
• NCBI Gene ID: 26088
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UJY5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

golgi associated, gamma adaptin ear containing, ARF binding protein 1 interacts with:

• adaptor related protein complex 1 associated regulatory protein
  aftiphilin
  ataxin 7 like 1
  centromere protein H
  centrosomal protein 44
  centrosomal protein 72
  chromosome 1 open reading frame 216
  coiled-coil domain containing 91
  cyclin dependent kinase like 3
  DiGeorge syndrome critical region gene 6 like
  dystrobrevin binding protein 1
  ethylmalonyl-CoA decarboxylase 1
  exocyst complex component 4
  FA core complex associated protein 100
  golgi associated, gamma adaptin ear containing, ARF binding protein 1
  inhibitor of growth family member 5
  limb and CNS expressed 1 like
  microtubule associated protein 1S
  NECAP endocytosis associated 2
  RAB guanine nucleotide exchange factor 1
  ring finger protein 11
  solute carrier family 38 member 7
  synaptosome associated protein 47
  TMEM9 domain family member B
  toll interacting protein
  transmembrane protein 17
  VPS18 core subunit of CORVET and HOPS complexes
  WASH complex subunit 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.