VPS54, VPS54 subunit of GARP complex

VPS54, VPS54 subunit of GARP complex

• This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms [provided by RefSeq, Jul 2008]

• Gene Synonyms (vacuolar protein sorting-associated protein 54, VPS54, GARP complex subunit, hepatocellular carcinoma protein 8, protein phosphatase 1, regulatory subunit 164, tumor antigen HOM-HCC-8, tumor antigen SLP-8p, vacuolar protein sorting 54 homolog, HCC8, PPP1R164, SLP-8p, VPS54L, WR, hVps54L,)
• NCBI Gene ID: 51542
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9P1Q0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

VPS54 subunit of GARP complex interacts with:

• armadillo like helical domain containing 3
  protein prenyltransferase alpha subunit repeat containing 1
  RAB1B, member RAS oncogene family
  UFM1 specific ligase 1
  VPS50 subunit of EARP/GARPII complex
  VPS53 subunit of GARP complex
  zinc finger containing ubiquitin peptidase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.