HSD17B12, hydroxysteroid 17-beta dehydrogenase 12

HSD17B12, hydroxysteroid 17-beta dehydrogenase 12

• This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. [provided by RefSeq, Oct 2011]

• Gene Synonyms (very-long-chain 3-oxoacyl-CoA reductase, 17-beta-HSD 12, 17-beta-hydroxysteroid dehydrogenase 12, 17beta-HSD type 12, 3-ketoacyl-CoA reductase, estradiol 17-beta-dehydrogenase 12, short chain dehydrogenase/reductase family 12C member 1, steroid dehydrogenase homolog, KAR, SDR12C1,)
• NCBI Gene ID: 51144
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q53GQ0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

hydroxysteroid 17-beta dehydrogenase 12 interacts with:

• autophagy related 16 like 1
  calreticulin 3
  egl-9 family hypoxia inducible factor 3
  ELOVL fatty acid elongase 1
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  histone deacetylase 11
  integrin alpha FG-GAP repeat containing 1
  limb development membrane protein 1 like
  membrane spanning 4-domains A4A
  MMS19 homolog, cytosolic iron-sulfur assembly component
  myotubularin related protein 14
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  pleckstrin homology domain containing A4
  RAB1B, member RAS oncogene family
  ring finger protein 157
  solute carrier family 15 member 3
  synoviolin 1
  tectonic family member 2
  translocase of outer mitochondrial membrane 22
  transmembrane and coiled-coil domains 1
  unc-93 homolog B1, TLR signaling regulator
  WW domain containing oxidoreductase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.