CPSF6, cleavage and polyadenylation specific factor 6

CPSF6, cleavage and polyadenylation specific factor 6

• The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]

• Gene Synonyms (cleavage and polyadenylation specificity factor subunit 6, CPSF 68 kDa subunit, cleavage and polyadenylation specific factor 6, 68kDa, cleavage and polyadenylation specificity factor 68 kDa subunit, cleavage factor Im complex 68 kDa subunit, pre-mRNA cleavage factor I, 68kD subunit, pre-mRNA cleavage factor Im (68kD), pre-mRNA cleavage factor Im 68 kDa subunit, protein HPBRII-4/7, CFIM, CFIM68, CFIM72, HPBRII-4, HPBRII-7,)
• NCBI Gene ID: 11052
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q16630
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cleavage and polyadenylation specific factor 6 interacts with:

• arginine and serine rich protein 1
  armadillo repeat containing 7
  bromodomain containing 7
  cap methyltransferase 1
  cleavage and polyadenylation specific factor 7
  coenzyme Q2, polyprenyltransferase
  coiled-coil domain containing 8
  cullin associated and neddylation dissociated 1
  gypsy retrotransposon integrase 1
  intersectin 2
  itchy E3 ubiquitin protein ligase
  jumonji domain containing 6, arginine demethylase and lysine hydroxylase
  kelch like family member 12
  LUC7 like 2, pre-mRNA splicing factor
  methyltransferase like 14
  myosin light chain 12B
  nucleoporin 107
  obscurin like cytoskeletal adaptor 1
  OTU deubiquitinase, ubiquitin aldehyde binding 2
  Parkinsonism associated deglycase
  PCF11 cleavage and polyadenylation factor subunit
  peptidylprolyl isomerase like 1
  poly(U) binding splicing factor 60
  potassium channel tetramerization domain containing 10
  pre-mRNA processing factor 40 homolog A
  protein phosphatase 4 regulatory subunit 3A
  pyrin and HIN domain family member 1
  RAD18 E3 ubiquitin protein ligase
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 31
  SMAD specific E3 ubiquitin protein ligase 1
  SNW domain containing 1
  staphylococcal nuclease and tudor domain containing 1
  SUZ12 polycomb repressive complex 2 subunit
  TBC1 domain family member 2
  TNFAIP3 interacting protein 2
  toll interacting protein
  U2 small nuclear RNA auxiliary factor 2
  ubiquilin 4
  ubiquitin specific peptidase 21
  vir like m6A methyltransferase associated
  WW domain binding protein 11
  WW domain binding protein 4
  WW domain containing E3 ubiquitin protein ligase 1
  WW domain containing E3 ubiquitin protein ligase 2
  WW domain containing oxidoreductase
  zinc finger and BTB domain containing 8B
  zinc finger MYND-type containing 19

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.