MYL12B, myosin light chain 12B

MYL12B, myosin light chain 12B

• The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (MLC-B, MRLC2, myosin regulatory light chain 12B, MLC-2, MLC-2A, MLC20, SHUJUN-1, myosin regulatory light chain 2, myosin regulatory light chain 2-B, smooth muscle isoform, myosin regulatory light chain 20 kDa, myosin regulatory light chain MRLC2, myosin, light chain 12B, regulatory,)
• NCBI Gene ID: 103910
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14950
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

myosin light chain 12B interacts with:

• agrin
  HAUS augmin like complex subunit 1
  leucine rich repeat kinase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.