CCT3, chaperonin containing TCP1 subunit 3

CCT3, chaperonin containing TCP1 subunit 3

• The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010]

• Gene Synonyms (T-complex protein 1 subunit gamma, T-complex protein 1, gamma subunit, TCP1 (t-complex-1) ring complex, polypeptide 5, chaperonin containing TCP1, subunit 3 (gamma), hTRiC5, CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5,)
• NCBI Gene ID: 7203
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KX11
  UNIPROT ID#>>P49368
  UNIPROT ID#>>Q59H77
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

chaperonin containing TCP1 subunit 3 interacts with:

• 2'-5'-oligoadenylate synthetase like
  AAR2 splicing factor
  actin beta like 2
  actin related protein 1B
  actin related protein 2
  actin related protein 3
  actin related protein 3B
  actin, beta
  activator of HSP90 ATPase activity 1
  anterior gradient 2, protein disulphide isomerase family member
  argonaute RISC catalytic component 3
  armadillo repeat containing 6
  ARP1 actin-related protein 1B, centractin beta
  autophagy and beclin 1 regulator 1
  autophagy related 16 like 1
  B9 domain containing 1
  beta-transducin repeat containing E3 ubiquitin protein ligase
  BUB3 mitotic checkpoint protein
  calmodulin-lysine N-methyltransferase
  cell division cycle 20
  cell division cycle 73
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 5
  chaperonin containing TCP1 subunit 6B
  chaperonin containing TCP1 subunit 7
  chaperonin containing TCP1 subunit 8
  chaperonin containing Tcp1, subunit 2 (beta)
  chaperonin containing Tcp1, subunit 4 (delta)
  chaperonin containing Tcp1, subunit 7 (eta)
  chaperonin containing Tcp1, subunit 8 (theta)
  chromobox 1
  chromosome 1 open reading frame 127
  chromosome 11 open reading frame 54
  cilia and flagella associated protein 300
  coiled-coil domain containing 8
  COP1 E3 ubiquitin ligase
  cortactin binding protein 2
  cullin 3
  cullin 7
  cyclin dependent kinase 11A
  cyclin dependent kinase 13
  cyclin-dependent kinase 1
  DDB1 and CUL4 associated factor 10
  DDB1 and CUL4 associated factor 11
  DDB1 and CUL4 associated factor 12
  DDB1 and CUL4 associated factor 12 like 2
  DDB1 and CUL4 associated factor 13
  DDB1 and CUL4 associated factor 4
  DDB1 and CUL4 associated factor 5
  DDB1 and CUL4 associated factor 7
  DDB1 and CUL4 associated factor 8
  denticleless E3 ubiquitin protein ligase
  denticleless E3 ubiquitin protein ligase homolog
  DEP domain containing 5, GATOR1 subcomplex subunit
  DnaJ heat shock protein family (Hsp40) member A4
  DnaJ heat shock protein family (Hsp40) member C7
  dynein 2 intermediate chain 2
  dynein axonemal intermediate chain 2
  EARP complex and GARP complex interacting protein 1
  EEF1A lysine methyltransferase 3
  egl-9 family hypoxia inducible factor 3
  EH domain containing 2
  electron transfer flavoprotein subunit beta lysine methyltransferase
  elongation factor Tu GTP binding domain containing 2
  embryonic ectoderm development
  ERBB receptor feedback inhibitor 1
  euchromatic histone lysine methyltransferase 2
  eukaryotic translation initiation factor 2B subunit beta
  family with sequence similarity 86 member B2
  Fas associated factor 1
  F-box and WD repeat domain containing 7
  F-box and WD repeat domain containing 8
  F-box protein 6
  FYVE and coiled-coil domain autophagy adaptor 1
  G protein subunit beta 1 like
  G protein subunit beta 5
  G3BP stress granule assembly factor 1
  gem nuclear organelle associated protein 4
  gigaxonin
  glucosidase II alpha subunit
  glutamate rich WD repeat containing 1
  guanine nucleotide binding protein (G protein), beta 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  heterogeneous nuclear ribonucleoprotein A0
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 11
  histone deacetylase 3
  histone deacetylase 5
  histone deacetylase 6
  host cell factor C2
  hypoxia inducible factor 1 subunit alpha inhibitor
  immunoglobulin superfamily member 8
  inhibitor of nuclear factor kappa B kinase subunit epsilon
  integrin alpha FG-GAP repeat containing 1
  ISG15 ubiquitin like modifier
  jumonji domain containing 4
  kelch domain containing 2
  kelch domain containing 8A
  kelch domain containing 8B
  kelch like family member 33
  kelch like family member 8
  kinase suppressor of ras 1
  kinesin family member 21A
  kinesin family member 21B
  L3MBTL histone methyl-lysine binding protein 2
  La ribonucleoprotein 7, transcriptional regulator
  leucine rich repeat containing 47
  ligand of numb-protein X 2
  lysine demethylase 4B
  methionyl aminopeptidase 2
  methylphosphate capping enzyme
  methyltransferase like 14
  methyltransferase like 18
  methyltransferase like 21C
  methyltransferase like 23
  methyltransferase like 3
  mirror-image polydactyly 1
  mitogen-activated protein kinase 13
  mitogen-activated protein kinase 15
  MKS transition zone complex subunit 1
  MOB family member 4, phocein
  MTOR associated protein, LST8 homolog
  NEDD1 gamma-tubulin ring complex targeting factor
  neural precursor cell expressed, developmentally down-regulated gene 1
  neutral sphingomyelinase activation associated factor
  nipsnap homolog 1
  nuclear RNA export factor 5
  nucleolar protein 10
  obscurin like cytoskeletal adaptor 1
  odontogenesis associated phosphoprotein
  O-linked N-acetylglucosamine (GlcNAc) transferase
  osteopetrosis associated transmembrane protein 1
  parkin coregulated
  patatin like phospholipase domain containing 1
  patatin like phospholipase domain containing 5
  phosducin like 3
  phosphatidylinositol 4-kinase type 2 beta
  phosphoethanolamine/phosphocholine phosphatase 1
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  POC1 centriolar protein A
  POC1 centriolar protein B
  poly(A) specific ribonuclease subunit PAN2
  polycomb group ring finger 6
  pre-mRNA processing factor 4
  pre-mRNA processing factor 8
  prolyl 4-hydroxylase subunit alpha 2
  proteasome 26S subunit, non-ATPase 14
  protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
  protein phosphatase 2 regulatory subunit Bdelta
  protein phosphatase 4 regulatory subunit 2
  protein phosphatase 4, catalytic subunit
  protein phosphatase 6, catalytic subunit
  protein phosphatase, Mg2+/Mn2+ dependent 1J
  PTEN induced kinase 1
  RAP2C, member of RAS oncogene family
  receptor interacting serine/threonine kinase 4
  RecQ like helicase 4
  regulatory associated protein of MTOR complex 1
  ring finger and CCCH-type domains 2
  ring finger and WD repeat domain 3
  ring finger protein 123
  ring finger protein 181
  ring finger protein 31
  RIO kinase 1
  RNA polymerase I and III subunit C
  SAMM50 sorting and assembly machinery component
  SEC31 homolog B, COPII coat complex component
  SEH1 like nucleoporin
  serine/threonine kinase 24
  serum/glucocorticoid regulated kinase 2
  SH3 domain binding protein 4
  sirtuin 7
  SNW domain containing 1
  spermine oxidase
  spindle apparatus coiled-coil protein 1
  STE20 related adaptor beta
  striatin 3
  striatin, calmodulin binding protein 3
  succinate-CoA ligase GDP-forming subunit beta
  suppressor of variegation 3-9 homolog 2
  SUZ12 polycomb repressive complex 2 subunit
  testis specific serine kinase 6
  tetratricopeptide repeat domain 27
  thioredoxin domain containing 9
  THO complex 3
  TNFAIP3 interacting protein 2
  transducin beta like 1 Y-linked
  transmembrane protein 41B
  tripartite motif containing 14
  tripartite motif containing 25
  tripartite motif containing 28
  tryptophanyl-tRNA synthetase 1
  tubulin alpha 1a
  tubulin alpha 1b
  tubulin alpha 1c
  tubulin alpha 3c
  tubulin alpha 3e
  tubulin alpha like 3
  tubulin beta 2B class IIb
  tubulin delta 1
  tubulin gamma 1
  tubulin gamma 2
  tubulin tyrosine ligase like 3
  tubulin tyrosine ligase like 9
  tubulin, alpha 3A
  tubulin, epsilon 1
  tubulin, gamma 1
  tyrosine kinase 2
  ubiquilin 2
  ubiquinol-cytochrome c reductase core protein 2
  ubiquitin associated and SH3 domain containing B
  ubiquitin C
  ubiquitin conjugating enzyme E2 M
  ubiquitin conjugating enzyme E2 Z
  ubiquitin C-terminal hydrolase L3
  UTP18 small subunit processome component
  valosin containing protein
  valyl-tRNA synthetase 1
  vascular cell adhesion molecule 1
  vav guanine nucleotide exchange factor 2
  vir like m6A methyltransferase associated
  von Hippel-Lindau tumor suppressor
  WD and tetratricopeptide repeats 1
  WD repeat containing antisense to TP53
  WD repeat domain 37
  WD repeat domain 46
  WD repeat domain 48
  WD repeat domain 5
  WD repeat domain 5B
  WD repeat domain 61
  WD repeat domain 70
  WD repeat domain 76
  WD repeat domain 77
  WD repeat domain 82
  WD repeat domain 83
  WD repeat domain 86
  WD repeat domain 92
  WD repeat domain, phosphoinositide interacting 2
  WW domain containing E3 ubiquitin protein ligase 2
  X-ray repair cross complementing 3
  Yes1 associated transcriptional regulator
  zinc finger and BTB domain containing 38
  zinc finger CCCH-type containing 7A
  zinc finger protein 598, E3 ubiquitin ligase
  zinc finger protein 746
  zinc ribbon domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.