STK24, serine/threonine kinase 24

STK24, serine/threonine kinase 24

• This gene encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

• Gene Synonyms (serine/threonine-protein kinase 24, STE20-like kinase 3, STE20-like kinase MST3, epididymis secretory protein Li 95, mammalian STE20-like protein kinase 3, serine/threonine kinase 24 (STE20 homolog, yeast), sterile 20-like kinase 3, HEL-S-95, MST3, MST3B, STE20, STK3,)
• NCBI Gene ID: 8428
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DR80
  UNIPROT ID#>>Q6P0Y1
  UNIPROT ID#>>Q9Y6E0
  UNIPROT ID#>>Q5U0E6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serine/threonine kinase 24 interacts with:

• ATPase H+ transporting V1 subunit C2
  calcium binding protein 39
  centrosomal protein 135
  centrosomal protein 19
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 5
  chaperonin containing TCP1 subunit 7
  chaperonin containing TCP1 subunit 8
  chromosome 4 open reading frame 19
  component of oligomeric golgi complex 5
  cortactin binding protein 2
  CTTNBP2 N-terminal like
  dynein light chain LC8-type 1
  FGFR1 oncogene partner 2
  G3BP stress granule assembly factor 2
  heterogeneous nuclear ribonucleoprotein A3
  isochorismatase domain containing 1
  junctophilin 3
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat kinase 2
  MAGI family member, X-linked
  methionine adenosyltransferase 2B
  MOB family member 4, phocein
  pleckstrin homology domain containing A4
  programmed cell death 10
  programmed cell death 6 interacting protein
  proline and serine rich 2
  protein disulfide isomerase family A member 4
  serine carboxypeptidase 1
  serine/threonine kinase 24
  serine/threonine kinase 25
  serine/threonine kinase 26
  serine/threonine kinase 38 like
  striatin 3
  striatin 4
  striatin interacting protein 1
  striatin interacting protein 1
  striatin interacting protein 2
  striatin, calmodulin binding protein 3
  suppressor of IKBKE 1
  synaptotagmin binding cytoplasmic RNA interacting protein
  tousled like kinase 2
  TRAF3 interacting protein 3
  tRNA methyltransferase 6
  tubulin beta class I
  WD repeat containing antisense to TP53
  zinc finger and BTB domain containing 24

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.