CEP135, centrosomal protein 135

CEP135, centrosomal protein 135

• This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8. [provided by RefSeq, Jun 2012]

• Gene Synonyms (centrosomal protein of 135 kDa, centrosomal protein 135kDa, centrosomal protein 4, centrosome protein cep135, CEP4, KIAA0635, MCPH8,)
• NCBI Gene ID: 9662
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q66GS9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

centrosomal protein 135 interacts with:

• 5'-3' exoribonuclease 1
  BLOC-1 related complex subunit 6
  C2 domain containing 3 centriole elongation regulator
  calmodulin regulated spectrin associated protein 1
  caspase recruitment domain family member 9
  centriolar coiled-coil protein 110
  centrosomal protein 120
  centrosomal protein 128
  centrosomal protein 131
  centrosomal protein 135
  centrosomal protein 152
  centrosomal protein 162
  centrosomal protein 170
  centrosomal protein 192
  centrosomal protein 20
  centrosomal protein 290
  centrosomal protein 295
  centrosomal protein 350
  centrosomal protein 43
  centrosomal protein 44
  centrosomal protein 55
  centrosomal protein 72
  centrosomal protein 85
  centrosomal protein 95
  centrosomal protein 97
  centrosome and spindle pole associated protein 1
  chromobox 6
  coiled-coil and C2 domain containing 1A
  coiled-coil domain containing 138
  coiled-coil domain containing 14
  coiled-coil domain containing 18
  coiled-coil domain containing 61
  coiled-coil domain containing 66
  coiled-coil domain containing 77
  COMMD3-BMI1 readthrough
  DEAH-box helicase 35
  decapping enzyme, scavenger
  ELKS/RAB6-interacting/CAST family member 1
  endosome associated trafficking regulator 1
  engulfment and cell motility 2
  eukaryotic translation elongation factor 1 alpha 1
  family with sequence similarity 83 member B
  family with sequence similarity 83 member H
  GEN1 Holliday junction 5' flap endonuclease
  glutamate receptor interacting protein 1
  G-patch domain containing 1
  HAUS augmin like complex subunit 1
  HAUS augmin like complex subunit 3
  HAUS augmin like complex subunit 4
  HAUS augmin like complex subunit 6
  HAUS augmin like complex subunit 7
  HAUS augmin like complex subunit 8
  heterogeneous nuclear ribonucleoprotein C like 1
  inhibitor of Bruton tyrosine kinase
  intraflagellar transport 74
  isochorismatase domain containing 1
  kelch like ECH associated protein 1
  KIAA0753
  KIAA1328
  KIAA1671
  kinesin family member 14
  kinesin family member 7
  leucine rich repeat containing 49
  leucine zipper tumor suppressor 2
  leucine zipper tumor suppressor family member 3
  MAP7 domain containing 3
  MCTS1 re-initiation and release factor
  mediator complex subunit 4
  microtubule associated protein RP/EB family member 1
  migration and invasion inhibitory protein
  mindbomb E3 ubiquitin protein ligase 1
  MIS18 kinetochore protein A
  M-phase phosphoprotein 9
  myotrophin
  NCK associated protein 5 like
  NEDD1 gamma-tubulin ring complex targeting factor
  neuron navigator 1
  ninein
  NME/NM23 family member 7
  nuclear receptor coactivator 5
  nudE neurodevelopment protein 1
  nudE neurodevelopment protein 1 like 1
  platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
  pleckstrin homology and RhoGEF domain containing G1
  progesterone immunomodulatory binding factor 1
  proline and serine rich 3
  proline rich coiled-coil 2B
  PX domain containing 1
  REST corepressor 1
  Rho GTPase activating protein 21
  rotatin
  SEC23 interacting protein
  signal induced proliferation associated 1 like 1
  signal induced proliferation associated 1 like 2
  signal induced proliferation associated 1 like 3
  spermatogenesis associated 2
  spermatogenesis associated 2 like
  spermatogenesis associated 24
  spermatogenesis associated 5
  spindle and centriole associated protein 1
  splicing regulatory glutamic acid and lysine rich protein 1
  SREK1 interacting protein 1
  SSX family member 2 interacting protein
  synemin
  TANK binding kinase 1
  taxilin alpha
  taxilin beta
  taxilin gamma
  TBC1 domain family member 19
  TBC1 domain family member 31
  testis expressed 9
  TNFAIP3 interacting protein 1
  TRAF family member associated NFKB activator
  transmembrane protein 160
  transmembrane protein 209
  trichoplein keratin filament binding
  trinucleotide repeat containing adaptor 6A
  trinucleotide repeat containing adaptor 6B
  tubulin polyglutamylase complex subunit 1
  tubulin tyrosine ligase like 5
  ubiquitin specific peptidase 54
  WD repeat containing, antisense to TP73
  WD repeat domain 83
  WD repeat domain 90
  XK related 4
  YTH N6-methyladenosine RNA binding protein 1
  zinc finger matrin-type 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.