NCOA5, nuclear receptor coactivator 5

NCOA5, nuclear receptor coactivator 5

• This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2017]

• Gene Synonyms (CIA, bA465L10.6, nuclear receptor coactivator 5, NCoA-5, coactivator independent of AF-2,)
• NCBI Gene ID: 57727
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HCD5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear receptor coactivator 5 interacts with:

• B9 domain containing 2
  coiled-coil domain containing 57
  family with sequence similarity 214 member B
  fused in sarcoma
  KH RNA binding domain containing, signal transduction associated 2
  meiosis/spermiogenesis associated 1
  nuclear receptor coactivator 5
  nudix hydrolase 12
  OTU deubiquitinase, ubiquitin aldehyde binding 2
  pyrin and HIN domain family member 1
  serine and arginine-rich splicing factor 1
  synaptotagmin 16
  TATA-box binding protein associated factor 15
  testis specific 10 interacting protein
  ubiquitin like 5
  zinc finger protein 326

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.