TNRC6A, trinucleotide repeat containing adaptor 6A

TNRC6A, trinucleotide repeat containing adaptor 6A

• This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]

• Gene Synonyms (trinucleotide repeat-containing gene 6A protein, CAG repeat protein 26, CTD-2540M10.1, EDIE, EMSY interactor protein, GW182 autoantigen, glycine-tryptophan protein of 182 kDa, trinucleotide repeat containing 6A, CAGH26, FAME6, GW1, GW182, TNRC6,)
• NCBI Gene ID: 27327
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NDV7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

trinucleotide repeat containing adaptor 6A interacts with:

• AHNAK nucleoprotein 2
  anaphase promoting complex subunit 1
  anaphase promoting complex subunit 4
  anaphase promoting complex subunit 5
  anaphase promoting complex subunit 7
  argonaute RISC catalytic component 3
  argonaute RISC component 4
  CCR4-NOT transcription complex subunit 11
  CCR4-NOT transcription complex subunit 6
  CCR4-NOT transcription complex subunit 6 like
  CCR4-NOT transcription complex subunit 7
  CDK5 regulatory subunit associated protein 3
  cell cycle and apoptosis regulator 2
  centrobin, centriole duplication and spindle assembly protein
  centromere protein J
  cleavage and polyadenylation specific factor 7
  eukaryotic translation initiation factor 2 alpha kinase 4
  FA complementation group M
  G2 and S-phase expressed 1
  GATA zinc finger domain containing 2A
  KIAA2013
  lysine methyltransferase 2C
  mediator complex subunit 4
  mindbomb E3 ubiquitin protein ligase 1
  N-acetyltransferase 10
  ninein
  paraspeckle component 1
  PAT1 homolog 1, processing body mRNA decay factor
  PCF11 cleavage and polyadenylation factor subunit
  poly(A) specific ribonuclease subunit PAN3
  salvador family WW domain containing protein 1
  SSX family member 2 interacting protein
  tankyrase 1 binding protein 1
  TNFAIP3 interacting protein 2
  tripartite motif containing 65
  ubiquitin protein ligase E3 component n-recognin 5
  WNK lysine deficient protein kinase 1
  zinc finger and BTB domain containing 10
  zinc finger CCCH-type containing 7A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.