STK25, serine/threonine kinase 25

STK25, serine/threonine kinase 25

• This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]

• Gene Synonyms (SOK1, YSK1, serine/threonine-protein kinase 25, Ste20, yeast homolog, ste20-like kinase, ste20/oxidant stress response kinase 1, sterile 20/oxidant stress-response kinase 1,)
• NCBI Gene ID: 10494
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R4B2
  UNIPROT ID#>>B4E185
  UNIPROT ID#>>B3KRS6
  UNIPROT ID#>>B4DMA5
  UNIPROT ID#>>Q96BA2
  UNIPROT ID#>>A0A0S2Z4Y2
  UNIPROT ID#>>B4DVS7
  UNIPROT ID#>>O00506
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serine/threonine kinase 25 interacts with:

• acyl-CoA dehydrogenase family member 11
  ADP ribosylation factor like GTPase 13B
  ARV1 homolog, fatty acid homeostasis modulator
  calcium binding protein 39
  centrosomal protein 70
  chromosome 4 open reading frame 19
  cortactin binding protein 2
  CTTNBP2 N-terminal like
  cyclin D1 binding protein 1
  dynein light chain LC8-type 1
  FGFR1 oncogene partner 2
  golgi reassembly stacking protein 1
  golgin A6 family like 9
  HBS1 like translational GTPase
  interactor of HORMAD1 1
  leucine rich repeat kinase 2
  metadherin
  mitochondrial poly(A) polymerase
  MOB family member 4, phocein
  pleckstrin homology domain containing A4
  programmed cell death 10
  proline and serine rich 2
  serine/threonine kinase 25
  serine/threonine kinase 26
  striatin 3
  striatin 4
  striatin interacting protein 1
  striatin interacting protein 2
  suppressor of IKBKE 1
  TAO kinase 1
  ubiquitin specific peptidase 36
  zinc finger DHHC-type palmitoyltransferase 17
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.