MKS1, MKS transition zone complex subunit 1

MKS1, MKS transition zone complex subunit 1

• The protein encoded by this gene localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

• Gene Synonyms (Meckel syndrome type 1 protein, POC12 centriolar protein homolog, BBS13, JBTS28, MES, MKS, POC12,)
• NCBI Gene ID: 54903
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z5Z2
  UNIPROT ID#>>H0Y2S2
  UNIPROT ID#>>B4DVC5
  UNIPROT ID#>>Q9NXB0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MKS transition zone complex subunit 1 interacts with:

• B9 domain containing 2
  chromosome 6 open reading frame 141
  coiled-coil and C2 domain containing 2A
  DEAD-box helicase 24
  dedicator of cytokinesis 5
  DnaJ heat shock protein family (Hsp40) member C11
  ectonucleotide pyrophosphatase/phosphodiesterase 6
  ectonucleotide pyrophosphatase/phosphodiesterase 7
  glutamine amidotransferase like class 1 domain containing 1
  HAUS augmin like complex subunit 7
  HAUS augmin like complex subunit 8
  lipase H
  Mab-21 domain containing 2
  NudC domain containing 2
  peptidylprolyl isomerase A like 4G
  phosducin like 3
  PIH1 domain containing 1
  pregnancy specific beta-1-glycoprotein 8
  RCC1 domain containing 1
  RNA polymerase II associated protein 3
  slingshot protein phosphatase 3
  sorting nexin family member 21
  sterile alpha motif domain containing 4B
  tectonic family member 1
  tectonic family member 2
  transmembrane protein 17
  transmembrane protein 231
  transmembrane protein 67
  TSPY like 6
  tubulin polyglutamylase complex subunit 1
  unc-45 myosin chaperone A
  YTH N6-methyladenosine RNA binding protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.