SPDL1, spindle apparatus coiled-coil protein 1

SPDL1, spindle apparatus coiled-coil protein 1

• This gene encodes a coiled-coil domain-containing protein that functions in mitotic spindle formation and chromosome segregation. The encoded protein plays a role in coordinating microtubule attachment by promoting recruitment of dynein proteins, and in mitotic checkpoint signaling. [provided by RefSeq, Jul 2016]

• Gene Synonyms (protein Spindly, arsenite-related gene 1 protein, coiled-coil domain-containing protein 99, rhabdomyosarcoma antigen MU-RMS-40.4A, rrhabdomyosarcoma antigen protein MU-RMS-40.4A, CCDC99,)
• NCBI Gene ID: 54908
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96EA4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

spindle apparatus coiled-coil protein 1 interacts with:

• actin beta like 2
  AHNAK nucleoprotein
  ankyrin repeat and SOCS box containing 16
  ankyrin repeat domain 34C
  ATP/GTP binding protein like 1
  ATPase family AAA domain containing 3B
  cadherin related 23
  capping protein inhibiting regulator of actin dynamics
  cell division cycle and apoptosis regulator 1
  centrosomal protein 126
  coiled-coil domain containing 50
  copine 5
  copine 8
  copine family member 9
  coronin 1B
  cortactin binding protein 2
  cullin associated and neddylation dissociated 1
  DBF4 zinc finger B
  DEAH-box helicase 40
  dermcidin
  dynein axonemal assembly factor 4
  epiplakin 1
  family with sequence similarity 234 member B
  F-box and WD repeat domain containing 7
  glutathione S-transferase theta 2B
  H2B.U histone 1
  H3.5 histone
  HAUS augmin like complex subunit 7
  mitochondrial ribosomal protein S9
  myosin heavy chain 14
  NIMA related kinase 9
  NOP2/Sun RNA methyltransferase 4
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  polybromo 1
  POTE ankyrin domain family member E
  protein phosphatase 1 regulatory subunit 18
  receptor transporter protein 5 (putative)
  Rho GTPase activating protein 9
  shugoshin 2
  SLAIN motif family member 1
  sosondowah ankyrin repeat domain family member A
  spindle and kinetochore associated complex subunit 3
  spindle apparatus coiled-coil protein 1
  sulfiredoxin 1
  taxilin beta
  terminal uridylyl transferase 7
  threonine synthase like 1
  THUMP domain containing 2
  transcriptional adaptor 2B
  tubulin alpha 4b
  tubulin beta 1 class VI
  tubulin beta 2B class IIb
  tubulin beta class I
  ubiquitin specific peptidase 45
  UDP-glucose glycoprotein glucosyltransferase 1
  vacuolar protein sorting 13 homolog D
  WD repeat domain 61
  WNK lysine deficient protein kinase 1
  WNK lysine deficient protein kinase 2
  WNK lysine deficient protein kinase 3
  YLP motif containing 1
  zinc finger protein 101

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.