POC1A, POC1 centriolar protein A

POC1A, POC1 centriolar protein A

• POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome. [provided by RefSeq, Sep 2012]

• Gene Synonyms (POC1 centriolar protein homolog A, WD repeat domain 51A, WD repeat-containing protein 51A, proteome of centriole protein 1A, PIX2, SOFT, WDR51A,)
• NCBI Gene ID: 25886
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NBT0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

POC1 centriolar protein A interacts with:

• 5'-3' exoribonuclease 1
  A-kinase interacting protein 1
  autophagy related 2B
  calmodulin regulated spectrin associated protein 1
  centromere protein H
  centrosomal protein 44
  centrosomal protein 85-like
  coiled-coil domain containing 66
  COMM domain containing 2
  COMM domain containing 4
  component of oligomeric golgi complex 6
  coronin 6
  crystallin beta-gamma domain containing 3
  cytoskeleton associated protein 2
  dynein axonemal assembly factor 2
  FAM161 centrosomal protein A
  FGFR1 oncogene partner 2
  G2 and S-phase expressed 1
  HAUS augmin like complex subunit 4
  inhibitor of Bruton tyrosine kinase
  intraflagellar transport 57
  La ribonucleoprotein 1B
  LTV1 ribosome biogenesis factor
  MAP7 domain containing 1
  MAP7 domain containing 3
  Mdm1 nuclear protein
  microtubule associated scaffold protein 1
  migration and invasion inhibitory protein
  myosin VC
  myosin, heavy polypeptide 10, non-muscle
  NIN1 (RPN12) binding protein 1 homolog
  pelota mRNA surveillance and ribosome rescue factor
  phosducin like 3
  pleckstrin homology domain containing A5
  POC1 centriolar protein B
  POC1 centriolar protein B
  POC5 centriolar protein
  POTE ankyrin domain family member F
  R3H domain and coiled-coil containing 1 like
  ring finger protein 168
  RIO kinase 1
  RNA polymerase II associated protein 3
  sialic acid acetylesterase
  SIL1 nucleotide exchange factor
  SLAIN motif family member 2
  spindle and kinetochore associated complex subunit 3
  testis specific serine kinase substrate
  trichoplein keratin filament binding
  tudor domain containing 3
  unc-45 myosin chaperone A
  WASH complex subunit 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.