EHD2, EH domain containing 2

EHD2, EH domain containing 2

• This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway. [provided by RefSeq, Jul 2008]

• Gene Synonyms (EH domain-containing protein 2, PAST homolog 2, PAST2,)
• NCBI Gene ID: 30846
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R0S6
  UNIPROT ID#>>Q9NZN4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EH domain containing 2 interacts with:

• cyclic GMP-AMP synthase
  DEAD-box helicase 56
  EH domain containing 2
  epsin 3
  glycerol-3-phosphate acyltransferase 4
  potassium channel tetramerization domain containing 15
  rabenosyn, RAB effector
  ring finger and FYVE like domain containing E3 ubiquitin protein ligase
  spermatogenesis associated 24
  TBC1 domain family member 23
  zinc finger and SCAN domain containing 29

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.