EIF3G, eukaryotic translation initiation factor 3 subunit G

EIF3G, eukaryotic translation initiation factor 3 subunit G

• This gene encodes a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex, which is required for initiation of protein translation. An N-terminal caspase cleavage product of the encoded protein may stimulate degradation of DNA. A mutation in this gene is associated with narcolepsy. [provided by RefSeq, Jul 2016]

• Gene Synonyms (eukaryotic translation initiation factor 3 subunit G, eukaryotic translation initiation factor 3 RNA-binding subunit, eukaryotic translation initiation factor 3 subunit p42, eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa, EIF3-P42, EIF3S4, eIF3-delta, eIF3-p44,)
• NCBI Gene ID: 8666
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75821
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

eukaryotic translation initiation factor 3 subunit G interacts with:

• ACD shelterin complex subunit and telomerase recruitment factor
  activator of HSP90 ATPase activity 1
  apoptosis inducing factor mitochondria associated 1
  BICD cargo adaptor 2
  cap methyltransferase 1
  ceramide kinase like
  DExD/H-box helicase 60
  elongation factor Tu GTP binding domain containing 2
  eukaryotic translation initiation factor 1
  eukaryotic translation initiation factor 1B
  eukaryotic translation initiation factor 3 subunit C like
  eukaryotic translation initiation factor 3 subunit G
  eukaryotic translation initiation factor 3 subunit H
  eukaryotic translation initiation factor 3 subunit I
  eukaryotic translation initiation factor 3 subunit K
  eukaryotic translation initiation factor 3 subunit L
  eukaryotic translation initiation factor 3 subunit M
  eukaryotic translation initiation factor 3, subunit A
  eukaryotic translation initiation factor 3, subunit E
  eukaryotic translation initiation factor 3, subunit I
  family with sequence similarity 9 member B
  G3BP stress granule assembly factor 1
  growth arrest and DNA damage inducible gamma
  HECT and RLD domain containing E3 ubiquitin protein ligase 2
  HEXIM P-TEFb complex subunit 1
  immunoglobulin superfamily member 8
  integrin alpha FG-GAP repeat containing 1
  intersectin 2
  kinase suppressor of ras 1
  La ribonucleoprotein 7, transcriptional regulator
  membrane palmitoylated protein 6
  methyltransferase like 3
  MIF4G domain containing
  M-phase phosphoprotein 6
  musashi RNA binding protein 2
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  poly(A) binding protein interacting protein 1
  poly(A) specific ribonuclease subunit PAN2
  protection of telomeres 1
  RecQ like helicase 4
  ribosomal protein L35
  ring finger and CCCH-type domains 2
  tripartite motif containing 14
  ubiquilin 2
  ubiquitin conjugating enzyme E2 M
  ubiquitin specific peptidase 3
  vir like m6A methyltransferase associated
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.