GADD45G, growth arrest and DNA damage inducible gamma

GADD45G, growth arrest and DNA damage inducible gamma

• This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CR6, DDIT2, GADD45gamma, GRP17, growth arrest and DNA damage-inducible protein GADD45 gamma, DDIT-2, DNA damage-inducible transcript 2 protein, GADD45-gamma, cytokine-responsive protein CR6, gadd-related protein, 17 kD,)
• NCBI Gene ID: 10912
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95257
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

growth arrest and DNA damage inducible gamma interacts with:

• actin filament associated protein 1 like 1
  actin related protein 2/3 complex subunit 5 like
  BEN domain containing 7
  biogenesis of lysosomal organelles complex 1 subunit 2
  centrosomal protein 57 like 1
  cilia and flagella associated protein 44
  dimethylarginine dimethylaminohydrolase 2
  DNA damage inducible transcript 4 like
  enkurin domain containing 1
  family with sequence similarity 156 member A
  family with sequence similarity 156 member B
  GADD45G interacting protein 1
  GRAM domain containing 4
  ligand dependent nuclear receptor interacting factor 1
  LUC7 like
  LUC7 like 2, pre-mRNA splicing factor
  mediator complex subunit 31
  midnolin
  peptidylprolyl isomerase like 1
  phosphorylated adaptor for RNA export
  protein inhibitor of activated STAT 4
  Ras association domain family member 10
  retinol dehydrogenase 13
  ribosomal RNA processing 7 homolog A
  RNA binding motif protein 48
  SH3 domain containing GRB2 like, endophilin B1
  SH3 domain containing GRB2 like, endophilin B2
  tRNA methyltransferase 2 homolog A
  zinc finger protein 579
  zinc finger protein 664
  zinc finger protein 763

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.