ACD, ACD shelterin complex subunit and telomerase recruitment factor

ACD, ACD shelterin complex subunit and telomerase recruitment factor

• This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]

• Gene Synonyms (adrenocortical dysplasia protein homolog, POT1 and TIN2-interacting protein, TIN2 interacting protein 1, adrenocortical dysplasia homolog, PIP1, PTOP, TINT1, TPP1,)
• NCBI Gene ID: 65057
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96AP0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ACD shelterin complex subunit and telomerase recruitment factor interacts with:

• actin filament associated protein 1 like 2
  annexin A8 like 1
  apolipoprotein B mRNA editing enzyme catalytic subunit 3F
  egl-9 family hypoxia inducible factor 3
  leucine rich repeat containing 25
  NudC domain containing 2
  PAGE family member 2
  POF1B actin binding protein
  TBC1 domain family member 10A
  tripartite motif containing 15
  zinc finger protein 790

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.