FBXO31, F-box protein 31

FBXO31, F-box protein 31

• This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

• Gene Synonyms (F-box only protein 31, SCF ubiquitin ligase specificity factor, putative breast cancer tumor-suppressor, FBX14, FBXO14, Fbx31, MRT45, pp2386,)
• NCBI Gene ID: 79791
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0C4DGU8
  UNIPROT ID#>>Q5XUX0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

F-box protein 31 interacts with:

• chromatin licensing and DNA replication factor 1
  chromosome 18 open reading frame 21
  cyclin Q
  DnaJ heat shock protein family (Hsp40) member C19
  glutamine and serine rich 1
  zinc finger CCHC-type containing 9

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.