CDT1, chromatin licensing and DNA replication factor 1

CDT1, chromatin licensing and DNA replication factor 1

• The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011]

• Gene Synonyms (DNA replication factor Cdt1, Double parked, Drosophila, homolog of, DUP, RIS2,)
• NCBI Gene ID: 81620
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H211
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

chromatin licensing and DNA replication factor 1 interacts with:

• chromatin licensing and DNA replication factor 1
  glutamate rich WD repeat containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.