RUVBL1, RuvB like AAA ATPase 1

RUVBL1, RuvB like AAA ATPase 1

• This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

• Gene Synonyms (ruvB-like 1, 49 kDa TATA box-binding protein-interacting protein, 49 kDa TBP-interacting protein, 54 kDa erythrocyte cytosolic protein, INO80 complex subunit H, RuvB (E coli homolog)-like 1, RuvB-like AAA ATPase, TAP54-alpha, TATA binding protein interacting protein 49 kDa, TIP60-associated protein 54-alpha, epididymis secretory sperm binding protein, nuclear matrix protein 238, pontin 52, ECP-54, ECP54, INO80H, NMP 238, NMP238, PONTIN, Pontin52, RVB1, TIH1, TIP49, TIP49A,)
• NCBI Gene ID: 8607
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y265
  UNIPROT ID#>>B3KRS7
  UNIPROT ID#>>E7ETR0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RuvB like AAA ATPase 1 interacts with:

• AAR2 splicing factor
  actin like 6B
  actin related protein 5
  actin related protein 6
  actin related protein 8
  actin, beta
  AHNAK nucleoprotein
  A-kinase anchoring protein 8
  anterior gradient 2, protein disulphide isomerase family member
  autophagy related 16 like 1
  B9 domain containing 1
  bromodomain containing 8
  calcium/calmodulin dependent protein kinase kinase 1
  cartilage acidic protein 1
  centrosomal protein 126
  centrosomal protein 250
  cereblon
  checkpoint kinase 2
  chromosome 12 open reading frame 45
  coiled-coil domain containing 8
  coiled-coil domain containing 87
  COP9 signalosome subunit 5
  craniofacial development protein 1
  cullin 7
  cullin associated and neddylation dissociated 1
  DEAD-box helicase 27
  DEAD-box helicase 42
  deleted in primary ciliary dyskinesia homolog (mouse)
  DNA methyltransferase 1 associated protein 1
  DnaJ heat shock protein family (Hsp40) member C17
  dynamin 1 like
  E1A binding protein p400
  E2F associated phosphoprotein
  E2F transcription factor 7
  ecdysoneless cell cycle regulator
  EEF1A lysine methyltransferase 3
  elongation factor Tu GTP binding domain containing 2
  embryonic ectoderm development
  enhancer of polycomb homolog 1
  enhancer of polycomb homolog 2
  euchromatic histone lysine methyltransferase 2
  Fas associated factor 1
  F-box protein 25
  F-box protein 46
  F-box protein 6
  F-box protein 7
  forkhead box R2
  GATA zinc finger domain containing 2A
  gem nuclear organelle associated protein 5
  glutamate rich WD repeat containing 1
  GPN-loop GTPase 1
  H2B clustered histone 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 5
  histone deacetylase 6
  Holliday junction recognition protein
  inhibitor of growth family member 3
  INO80 complex ATPase subunit
  INO80 complex subunit B
  INO80 complex subunit C
  INO80 complex subunit D
  INO80 complex subunit E
  integrator complex subunit 9
  integrin alpha FG-GAP repeat containing 1
  IQ motif containing GTPase activating protein 1
  JAZF zinc finger 1
  kinase suppressor of ras 1
  La ribonucleoprotein 7, transcriptional regulator
  lymphoid enhancer binding factor 1
  lysine acetyltransferase 5
  macroH2A.1 histone
  matrin 3
  mbt domain containing 1
  mediator complex subunit 12
  mediator complex subunit 15
  mediator complex subunit 7
  mediator complex subunit 9
  methylphosphate capping enzyme
  methyltransferase like 18
  methyltransferase like 3
  microspherule protein 1
  minichromosome maintenance 9 homologous recombination repair factor
  mortality factor 4 like 1
  mortality factor 4 like 2
  MRG domain binding protein
  MYST/Esa1 associated factor 6
  NOP58 ribonucleoprotein
  nuclear FMR1 interacting protein 1
  nuclear RNA export factor 1
  nucleoside-triphosphatase, cancer-related
  obscurin like cytoskeletal adaptor 1
  osteopetrosis associated transmembrane protein 1
  p53 and DNA damage regulated 1
  PAF1 homolog, Paf1/RNA polymerase II complex component
  pelota mRNA surveillance and ribosome rescue factor
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 1
  poly(A) specific ribonuclease subunit PAN2
  poly(rC) binding protein 3
  prefoldin 2
  pre-mRNA processing factor 31
  pre-mRNA processing factor 8
  pre-mRNA processing factor 8
  proline, glutamate and leucine rich protein 1
  proline-serine-threonine phosphatase interacting protein 1
  protein phosphatase methylesterase 1
  RAD18 E3 ubiquitin protein ligase
  RecQ like helicase 4
  regulatory associated protein of MTOR complex 1
  RIO kinase 1
  RNA binding motif protein 8A
  RNA polymerase I and III subunit C
  RNA polymerase I subunit A
  RNA polymerase II associated protein 3
  RNA polymerase III subunit A
  RTF1 homolog, Paf1/RNA polymerase II complex component
  RuvB like AAA ATPase 1
  RuvB like AAA ATPase 2
  RuvB-like protein 2
  serine and arginine rich splicing factor 11
  SET domain containing 1A, histone lysine methyltransferase
  SHQ1, H/ACA ribonucleoprotein assembly factor
  sirtuin 3
  sirtuin 6
  small nuclear ribonucleoprotein U5 subunit 200
  SMG1 nonsense mediated mRNA decay associated PI3K related kinase
  SMG8 nonsense mediated mRNA decay factor
  SMG9 nonsense mediated mRNA decay factor
  Snf2 related CREBBP activator protein
  SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
  SNW domain containing 1
  survival motor neuron domain containing 1
  SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
  TCF3 fusion partner
  TELO2 interacting protein 1
  TELO2 interacting protein 2
  telomere maintenance 2
  testis expressed 101
  thyroid hormone receptor interactor 4
  TNFAIP3 interacting protein 2
  transmembrane p24 trafficking protein 9
  transport and golgi organization 6 homolog
  tripartite motif containing 28
  tripartite motif containing 29
  tubulin beta 4B class IVb
  tubulin beta class I
  tumor suppressing subtransferable candidate 4
  U2 small nuclear RNA auxiliary factor 2
  ubiquilin 2
  ubiquitin conjugating enzyme E2 L6
  ubiquitin conjugating enzyme E2 M
  ubiquitin C-terminal hydrolase L5
  ubiquitin specific peptidase 49
  UBX domain protein 6
  URI1 prefoldin like chaperone
  vir like m6A methyltransferase associated
  WD repeat and coiled coil containing
  WD repeat domain 92
  WW domain containing E3 ubiquitin protein ligase 2
  Yes1 associated transcriptional regulator
  zinc finger and BTB domain containing 7A
  zinc finger HIT-type containing 1
  zinc finger HIT-type containing 3
  zinc finger HIT-type containing 6
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.