KAT5, lysine acetyltransferase 5

KAT5, lysine acetyltransferase 5

• The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, ZC2HC5, cPLA2, histone acetyltransferase KAT5, 60 kDa Tat-interactive protein, HIV-1 Tat interactive protein, 60kDa, K(lysine) acetyltransferase 5, K-acetyltransferase 5, Tat interacting protein, 60kDa, cPLA(2)-interacting protein, cPLA2 interacting protein, histone acetyltransferase HTATIP,)
• NCBI Gene ID: 10524
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R597
  UNIPROT ID#>>A0A024R5E8
  UNIPROT ID#>>Q92993
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lysine acetyltransferase 5 interacts with:

• 2-oxoglutarate and iron dependent oxygenase domain containing 2
  adenine nucleotide translocase lysine methyltransferase
  angiopoietin like 4
  argonaute RISC catalytic component 2
  bromodomain containing 8
  BTB domain and CNC homolog 2
  caveolae associated protein 1
  CDK5 regulatory subunit associated protein 2
  centrosomal protein 126
  centrosomal protein 70
  chaperonin containing TCP1 subunit 7
  chromobox 8
  chromosome 1 open reading frame 131
  chromosome 1 open reading frame 174
  coiled-coil domain containing 106
  coiled-coil domain containing 125
  coiled-coil domain containing 136
  coiled-coil domain containing 8
  cysteine rich with EGF like domains 1
  deoxynucleotidyltransferase terminal interacting protein 2
  DNA methyltransferase 1 associated protein 1
  dual specificity phosphatase 23
  dynein axonemal assembly factor 6
  E1A binding protein p400
  enhancer of polycomb homolog 1
  enhancer of polycomb homolog 2
  FAM161 centrosomal protein A
  family with sequence similarity 135 member B
  FCH and mu domain containing endocytic adaptor 1
  forkhead box O6
  forkhead box P3
  forkhead box R1
  forkhead box R2
  G kinase anchoring protein 1
  G protein-coupled receptor 156
  gem nuclear organelle associated protein 7
  germ cell-less 1, spermatogenesis associated
  germ cell-less 2, spermatogenesis associated
  GRB10 interacting GYF protein 1
  growth arrest and DNA damage inducible gamma
  guided entry of tail-anchored proteins factor 4
  H2B clustered histone 1
  H3 clustered histone 14
  H4 histone 16
  heat shock transcription factor 2 binding protein
  histone deacetylase 7
  homeobox containing 1
  hyaluronan binding protein 4
  IKAROS family zinc finger 3
  inhibitor of growth family member 3
  intraflagellar transport 20
  jade family PHD finger 1
  karyopherin subunit alpha 6
  keratin 40
  keratin associated protein 10-3
  keratin associated protein 10-9
  leucine rich repeat containing 42
  leucine zipper tumor suppressor 1
  leucine zipper tumor suppressor 2
  ligand dependent nuclear receptor interacting factor 1
  LON peptidase N-terminal domain and ring finger 1
  lysine acetyltransferase 5
  mbt domain containing 1
  microcephalin 1
  microtubule associated protein RP/EB family member 1
  microtubule associated scaffold protein 2
  mitofusin 1
  mortality factor 4 like 1
  MRG domain binding protein
  MYST/Esa1 associated factor 6
  NDUFA4 mitochondrial complex associated like 2
  ninein like
  nucleosome assembly protein 1 like 5
  nucleotide binding oligomerization domain containing 2
  PC4 and SFRS1 interacting protein 1
  placenta enriched 1
  pleckstrin homology domain containing A4
  potassium channel tetramerization domain containing 7
  PR/SET domain 6
  proline and serine rich 2
  protein phosphatase 1 regulatory subunit 16A
  refilin B
  ribosomal oxygenase 1
  ring finger and CHY zinc finger domain containing 1
  RNA polymerase III subunit F
  RuvB like AAA ATPase 2
  RuvB-like protein 1
  RuvB-like protein 2
  sec1 family domain containing 1
  secernin 2
  shisa family member 6
  sirtuin 1
  SNAP associated protein
  Snf2 related CREBBP activator protein
  SSX family member 2 interacting protein
  stathmin 3
  SUMO specific peptidase 6
  synaptonemal complex central element protein 1
  transforming growth factor beta regulated gene 1
  tribbles pseudokinase 3
  tripartite motif containing 29
  tripartite motif containing 68
  tuftelin interacting protein 11
  ubiquitin associated and SH3 domain containing B
  ubiquitin like with PHD and ring finger domains 1
  ubiquitin like with PHD and ring finger domains 2
  uracil phosphoribosyltransferase homolog
  uridine-cytidine kinase 1 like 1
  YJU2 splicing factor homolog
  zinc finger and BTB domain containing 1
  zinc finger and BTB domain containing 2
  zinc finger and BTB domain containing 49
  zinc finger and BTB domain containing 7B
  zinc finger and BTB domain containing 8A
  zinc finger and SCAN domain containing 4
  zinc finger C2HC-type containing 1C
  zinc finger protein 417
  zinc finger protein 511
  zinc finger protein 513
  zinc finger protein 526
  zinc finger protein 668
  zinc finger protein 692

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.