AGO2, argonaute RISC catalytic component 2

AGO2, argonaute RISC catalytic component 2

• This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

• Gene Synonyms (protein argonaute-2, PAZ Piwi domain protein, argonaute 2, RISC catalytic component, cancer susceptibility candidate 7, cancer susceptibility candidate 7 (non-protein coding), eukaryotic translation initiation factor 2C, 2, long intergenic non-protein coding RNA 980, protein slicer, CASC7, EIF2C2, LINC00980, PPD, Q10,)
• NCBI Gene ID: 27161
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UKV8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

argonaute RISC catalytic component 2 interacts with:

• ankyrin repeat and SOCS box containing 2
  argonaute RISC catalytic component 2
  argonaute RISC catalytic component 3
  argonaute RISC component 4
  baculoviral IAP repeat containing 6
  CCR4-NOT transcription complex subunit 6
  CCR4-NOT transcription complex subunit 6 like
  CCR4-NOT transcription complex subunit 7
  cereblon
  cilia and flagella associated protein 46
  COBW domain containing 2
  cullin associated and neddylation dissociated 1
  decapping mRNA 1A
  decapping mRNA 2
  DExH-box helicase 58
  DnaJ heat shock protein family (Hsp40) member A4
  eukaryotic elongation factor 2 kinase
  family with sequence similarity 166 member B
  formin homology 2 domain containing 1
  G protein-coupled receptor associated sorting protein 2
  gem nuclear organelle associated protein 4
  gremlin 2, DAN family BMP antagonist
  heparan sulfate 6-O-sulfotransferase 2
  interferon regulatory factor 2 binding protein like
  kelch like family member 29
  kelch repeat and BTB domain containing 8
  leucine rich repeat kinase 2
  mex-3 RNA binding family member D
  mindbomb E3 ubiquitin protein ligase 1
  myogenesis regulating glycosidase (putative)
  myosin light chain kinase 2
  myosin light chain, phosphorylatable, fast skeletal muscle
  nanos C2HC-type zinc finger 1
  ORC ubiquitin ligase 1
  PAF1 homolog, Paf1/RNA polymerase II complex component
  phosphatidylcholine transfer protein
  phosphatidylethanolamine binding protein 4
  pleckstrin homology domain containing A4
  prostate transmembrane protein, androgen induced 1
  ring finger and CCCH-type domains 2
  RIO kinase 1
  SCY1 like pseudokinase 1
  sorting nexin 9
  TANK binding kinase 1
  tau tubulin kinase 2
  transmembrane protein 64
  trinucleotide repeat containing adaptor 6A
  trinucleotide repeat containing adaptor 6C
  tripartite motif containing 71
  tRNA methyltransferase 1
  ubiquitin protein ligase E3 component n-recognin 5
  ubiquitin specific peptidase 47
  VPS37C subunit of ESCRT-I
  YTH N6-methyladenosine RNA binding protein 1
  zinc finger and BTB domain containing 10
  zinc finger CCCH-type containing 7A
  zinc finger CCCH-type containing, antiviral 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.