PPP1R16A, protein phosphatase 1 regulatory subunit 16A

PPP1R16A, protein phosphatase 1 regulatory subunit 16A

• Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while the phosphorylation of other MYPT members results in PP1c inactivation, phosphorylation of the encoded protein by protein kinase A results in PP1c activation. [provided by RefSeq, Jan 2020]

• Gene Synonyms (protein phosphatase 1 regulatory subunit 16A, myosin phosphatase-targeting subunit 3, protein phosphatase 1, regulatory (inhibitor) subunit 16A, MYPT3,)
• NCBI Gene ID: 84988
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96I34
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 1 regulatory subunit 16A interacts with:

• ataxin 7 like 2
  ATP23 metallopeptidase and ATP synthase assembly factor homolog
  basic leucine zipper ATF-like transcription factor 2
  chromosome 1 open reading frame 216
  coiled-coil domain containing 116
  creatine kinase, mitochondrial 1A
  IQ motif containing GTPase activating protein 3
  keratin associated protein 19-5
  mitochondrial coiled-coil domain 1
  protein phosphatase 1 regulatory subunit 16A
  refilin B

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