PRDM6, PR/SET domain 6

PRDM6, PR/SET domain 6

• The protein encoded by this gene is a transcriptional repressor and a member of the PRDM family. Family members contain a PR domain and multiple zinc-finger domains. The encoded protein is involved in regulation of vascular smooth muscle cells (VSMC) contractile proteins. Mutations in this gene result in patent ductus arteriosus 3 (PDA3). [provided by RefSeq, Apr 2017]

• Gene Synonyms (putative histone-lysine N-methyltransferase PRDM6, PR domain 6, PR domain containing 6, PR domain-containing protein 6, PR-domain zinc finger protein 6, KMT8C, PDA3, PRISM,)
• NCBI Gene ID: 93166
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NQX0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PR/SET domain 6 interacts with:

• ataxin 7 like 2
  BANF family member 2
  centrosomal protein 57 like 1
  coiled-coil domain containing 57
  forkhead box D4 like 1
  glutaredoxin and cysteine rich domain containing 1
  IQ motif and ubiquitin domain containing
  PIH1 domain containing 2
  PR/SET domain 6
  synaptonemal complex central element protein 3
  tektin 4
  testis specific 10 interacting protein
  ubiquitin specific peptidase 54

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.