SYCE1, synaptonemal complex central element protein 1

SYCE1, synaptonemal complex central element protein 1

• This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

• Gene Synonyms (C10orf94, CT76, POF12, SPGF15, synaptonemal complex central element protein 1, cancer/testis antigen 76, epididymis secretory sperm binding protein,)
• NCBI Gene ID: 93426
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0B4J1R9
  UNIPROT ID#>>Q8N0S2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

synaptonemal complex central element protein 1 interacts with:

• chibby family member 2
  cilia and flagella associated protein 100
  exocyst complex component 8
  FAM161 centrosomal protein B
  HAUS augmin like complex subunit 1
  IQ motif and ubiquitin domain containing
  Morf4 family associated protein 1 like 1
  spindle and kinetochore associated complex subunit 1
  syntaxin 19

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