PELP1, proline, glutamate and leucine rich protein 1

PELP1, proline, glutamate and leucine rich protein 1

• This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

• Gene Synonyms (MNAR, P160, proline-, glutamic acid- and leucine-rich protein 1, modulator of non-genomic activity of estrogen receptor, proline and glutamic acid rich nuclear protein, transcription factor HMX3,)
• NCBI Gene ID: 27043
• Species: Homo sapiens (Human)
• UNIPROT ID#>>C9JFV4
  UNIPROT ID#>>B4DEX7
  UNIPROT ID#>>E7EV54
  UNIPROT ID#>>B4DR36
  UNIPROT ID#>>Q8IZL8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

proline, glutamate and leucine rich protein 1 interacts with:

• BCAS3 microtubule associated cell migration factor
  cyclic GMP-AMP synthase
  cyclin dependent kinase 11A
  eukaryotic translation initiation factor 3, subunit I
  forkhead box Q1
  H2B clustered histone 1
  HIV-1 Tat specific factor 1
  LAS1 like ribosome biogenesis factor
  leucine rich repeat containing G protein-coupled receptor 4
  microtubule associated protein 1 light chain 3 alpha
  nucleolar protein 9
  pleckstrin homology domain containing A4
  pyrin and HIN domain family member 1
  sirtuin 7
  SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
  testis expressed 10
  WD repeat domain 18

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.