HTATSF1, HIV-1 Tat specific factor 1

HTATSF1, HIV-1 Tat specific factor 1

• The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009]

• Gene Synonyms (HIV Tat-specific factor 1, HIV TAT specific factor 1, cofactor required for Tat activation of HIV-1 transcription, TAT-SF1, TATSF1, dJ196E23.2,)
• NCBI Gene ID: 27336
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43719
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

HIV-1 Tat specific factor 1 interacts with:

• centrosomal protein 128
  FLYWCH-type zinc finger 1
  forty-two-three domain containing 1
  H3 clustered histone 15
  HIV-1 Tat specific factor 1
  integrin alpha FG-GAP repeat containing 1
  katanin catalytic subunit A1 like 2
  La ribonucleoprotein 7, transcriptional regulator
  leucine rich repeat kinase 2
  methyltransferase like 3
  niban apoptosis regulator 2
  nuclear assembly factor 1 ribonucleoprotein
  PTEN induced kinase 1
  pyrin and HIN domain family member 1
  splicing factor 3a, subunit 1
  transcription elongation factor A N-terminal and central domain containing 2
  zinc finger protein 512B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.