IGF2BP1, insulin like growth factor 2 mRNA binding protein 1

IGF2BP1, insulin like growth factor 2 mRNA binding protein 1

• This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

• Gene Synonyms (CRD-BP, CRDBP, IMP-1, IMP1, VICKZ1, ZBP1, insulin-like growth factor 2 mRNA-binding protein 1, IGF-II mRNA-binding protein 1, IGF2 mRNA-binding protein 1, VICKZ family member 1, ZBP-1, coding region determinant-binding protein, insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP, zipcode-binding protein 1,)
• NCBI Gene ID: 10642
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NZI8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

insulin like growth factor 2 mRNA binding protein 1 interacts with:

• 2-oxoglutarate and iron dependent oxygenase domain containing 1
  ADP ribosylation factor GTPase activating protein 2
  argonaute RISC component 4
  bromodomain containing 7
  CD2 associated protein
  centrosomal protein 250
  chromobox 6
  chromobox 8
  coiled-coil domain containing 8
  COP9 signalosome subunit 5
  C-type lectin domain containing 14A
  cullin associated and neddylation dissociated 1
  developmental pluripotency-associated 3
  dual specificity phosphatase 14
  euchromatic histone lysine methyltransferase 2
  eukaryotic translation initiation factor 3, subunit E
  Fas associated factor 1
  F-box protein 32
  F-box protein 6
  fermitin family member 2
  G1 to S phase transition 2
  HAUS augmin like complex subunit 2
  histone deacetylase 8
  insulin like growth factor 2 mRNA binding protein 2
  insulin like growth factor 2 mRNA binding protein 3
  integrin alpha FG-GAP repeat containing 1
  KH RNA binding domain containing, signal transduction associated 2
  La ribonucleoprotein 7, transcriptional regulator
  makorin ring finger protein 1
  mannosidase alpha class 1B member 1
  methylphosphate capping enzyme
  mitochondrial ribosomal protein S34
  neutral cholesterol ester hydrolase 1
  obscurin like cytoskeletal adaptor 1
  pleckstrin homology domain containing A4
  poly(U) binding splicing factor 60
  potassium channel tetramerization domain containing 10
  PTEN induced kinase 1
  RAB1B, member RAS oncogene family
  ribosome biogenesis regulator 1 homolog
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 31
  RIO kinase 1
  RNA polymerase II associated protein 1
  RPTOR independent companion of MTOR complex 2
  SEC23 interacting protein
  SEC31 homolog A, COPII coat complex component
  secretion associated Ras related GTPase 1A
  SET and MYND domain containing 2
  signal recognition particle 72
  solute carrier family 30 member 5
  TBL1X receptor 1
  TNFAIP3 interacting protein 2
  trafficking protein particle complex 12
  trafficking protein particle complex 13
  trafficking protein particle complex 5
  tubulin gamma complex associated protein 2
  tubulin gamma complex associated protein 4
  ubiquilin 2
  ubiquitin conjugating enzyme E2 S
  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
  VPS53 subunit of GARP complex
  WW domain containing E3 ubiquitin protein ligase 2
  WW domain containing oxidoreductase
  Y box protein 1
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.