CLEC14A, C-type lectin domain containing 14A

CLEC14A, C-type lectin domain containing 14A

• This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012]

• Gene Synonyms (C-type lectin domain family 14 member A, ClECT and EGF-like domain containing protein, epidermal growth factor receptor 5, C14orf27, CEG1, EGFR-5,)
• NCBI Gene ID: 161198
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86T13
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

C-type lectin domain containing 14A interacts with:

• LHFPL tetraspan subfamily member 5
  PGAM family member 5, mitochondrial serine/threonine protein phosphatase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.