IGF2BP2, insulin like growth factor 2 mRNA binding protein 2

IGF2BP2, insulin like growth factor 2 mRNA binding protein 2

• This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]

• Gene Synonyms (IMP-2, IMP2, VICKZ2, insulin-like growth factor 2 mRNA-binding protein 2, IGF-II mRNA-binding protein 2, IGF2 mRNA-binding protein 2, VICKZ family member 2,)
• NCBI Gene ID: 10644
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3FTN5
  UNIPROT ID#>>Q9Y6M1
  UNIPROT ID#>>B4DKT5
  UNIPROT ID#>>F8W930
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

insulin like growth factor 2 mRNA binding protein 2 interacts with:

• bromodomain containing 7
  cap methyltransferase 1
  centriolin
  chromobox 6
  chromobox 8
  coiled-coil domain containing 8
  C-type lectin domain containing 14A
  cullin associated and neddylation dissociated 1
  dual specificity phosphatase 14
  Fas binding factor 1
  La ribonucleoprotein 7, transcriptional regulator
  methylphosphate capping enzyme
  mitogen-activated protein kinase 13
  pleckstrin homology domain containing A4
  poly(U) binding splicing factor 60
  PTEN induced kinase 1
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  salvador family WW domain containing protein 1
  sirtuin 7
  TAR DNA binding protein
  TNFAIP3 interacting protein 2
  vir like m6A methyltransferase associated
  WW domain containing E3 ubiquitin protein ligase 2
  WW domain containing oxidoreductase
  zinc finger CCCH-type containing 7A
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.