VDAC2, voltage dependent anion channel 2

VDAC2, voltage dependent anion channel 2

• This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

• Gene Synonyms (voltage-dependent anion-selective channel protein 2, epididymis secretory sperm binding protein, outer mitochondrial membrane protein porin 2, POR,)
• NCBI Gene ID: 7417
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DKM5
  UNIPROT ID#>>P45880
  UNIPROT ID#>>A0A024QZT0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

voltage dependent anion channel 2 interacts with:

• AAR2 splicing factor
  acetyl-CoA acyltransferase 2
  ADP ribosylation factor like GTPase 8B
  AKT interacting protein
  aminoadipate-semialdehyde synthase
  ankyrin repeat domain 34C
  anterior gradient 2, protein disulphide isomerase family member
  apoptosis inducing factor mitochondria associated 1
  ATP binding cassette subfamily C member 3
  ATP synthase membrane subunit f
  ATPase H+ transporting V0 subunit d1
  ATPase H+ transporting V1 subunit F
  ATPase H+ transporting V1 subunit H
  autophagy related 16 like 1
  B cell receptor associated protein 31
  Bet1 golgi vesicular membrane trafficking protein
  CCCTC-binding factor
  CDGSH iron sulfur domain 1
  CDGSH iron sulfur domain 2
  centrosomal protein 43
  coenzyme Q2, polyprenyltransferase
  complement component 1, q subcomponent binding protein
  cullin 9
  cyclase associated actin cytoskeleton regulatory protein 1
  cytochrome b5 reductase 1
  cytochrome c oxidase assembly factor 3
  cytochrome c oxidase subunit 7A2 like
  cytochrome c, somatic
  density regulated re-initiation and release factor
  developmental pluripotency-associated 3
  DnaJ heat shock protein family (Hsp40) member C10
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  ER membrane protein complex subunit 1
  ER membrane protein complex subunit 2
  ezrin
  FAD dependent oxidoreductase domain containing 2
  family with sequence similarity 162 member A
  Fas associated factor 1
  Fas associated factor family member 2
  F-box and leucine rich repeat protein 6
  F-box protein 6
  G protein subunit beta 4
  glucosidase II alpha subunit
  golgi transport 1B
  HECT and RLD domain containing E3 ubiquitin protein ligase 2
  histone deacetylase 5
  huntingtin
  ilvB acetolactate synthase like
  inner membrane mitochondrial protein
  insulin like growth factor 2 mRNA binding protein 1
  IQ motif containing GTPase activating protein 1
  jagunal homolog 1
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat kinase 2
  limb development membrane protein 1 like
  magnesium transporter 1
  mannosyl-oligosaccharide glucosidase
  mediator complex subunit 23
  mediator of DNA damage checkpoint 1
  membrane magnesium transporter 1
  metaxin 2
  metaxin 2
  methyltransferase like 14
  mitochondrial carrier 1
  mitochondrial carrier 2
  mucolipin 1
  myoferlin
  myosin light chain 12A
  myosin XIX
  NADH:ubiquinone oxidoreductase core subunit S7
  NADH:ubiquinone oxidoreductase subunit A12
  NEDD4 like E3 ubiquitin protein ligase
  NIMA related kinase 11
  nipsnap homolog 1
  nucleotide binding oligomerization domain containing 2
  OCIA domain containing 2
  par-6 family cell polarity regulator beta
  PHD finger protein 8
  PIH1 domain containing 1
  pleckstrin homology and RhoGEF domain containing G5
  pleckstrin homology domain containing A2
  pleckstrin homology domain containing A4
  plexin B2
  POTE ankyrin domain family member F
  procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
  prohibitin 2
  prolactin regulatory element binding
  prolyl 4-hydroxylase subunit alpha 2
  proteasome activator subunit 3
  PTEN induced kinase 1
  RAB5 interacting factor
  RAB5C, member RAS oncogene family
  RAB7A, member RAS oncogene family
  RCC1 and BTB domain containing protein 1
  RecQ like helicase 4
  regulator of microtubule dynamics 3
  retention in endoplasmic reticulum sorting receptor 1
  saccharopine dehydrogenase (putative)
  septin 11
  serine incorporator 3
  sideroflexin 3
  solute carrier family 15 member 3
  solute carrier family 25 member 11
  sphingosine-1-phosphate lyase 1
  staphylococcal nuclease and tudor domain containing 1
  stonin 2
  SURP and G-patch domain containing 1
  syntaxin 12
  syntaxin 7
  thioredoxin related transmembrane protein 1
  THO complex 6
  TNF receptor associated protein 1
  trafficking protein particle complex 11
  trans-2,3-enoyl-CoA reductase
  trans-golgi network protein 2
  translocase of outer mitochondrial membrane 20
  translocase of outer mitochondrial membrane 40
  translocase of outer mitochondrial membrane 5
  transmembrane p24 trafficking protein 2
  transmembrane protein 109
  transmembrane protein 205
  transmembrane protein 63B
  tripartite motif containing 33
  tubulin alpha 1a
  tweety family member 3
  U2 small nuclear RNA auxiliary factor 2
  ubiquinol-cytochrome c reductase complex III subunit VII
  unc-93 homolog B1, TLR signaling regulator
  UTP14A small subunit processome component
  VAMP associated protein A
  vir like m6A methyltransferase associated
  voltage dependent anion channel 3
  WW domain containing oxidoreductase
  zinc finger protein 454
  zinc finger protein 598, E3 ubiquitin ligase
  zinc finger protein 782
  zinc finger RNA binding protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.