CDC34, cell division cycle 34, ubiqiutin conjugating enzyme

CDC34, cell division cycle 34, ubiqiutin conjugating enzyme

• The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ubiquitin-conjugating enzyme E2 R1, (E3-independent) E2 ubiquitin-conjugating enzyme R1, E2 ubiquitin-conjugating enzyme R1, cell division cycle 34 homolog, ubiquitin carrier protein, ubiquitin-conjugating enzyme E2-32 KDA complementing, ubiquitin-conjugating enzyme E2-CDC34, ubiquitin-protein ligase R1, E2-CDC34, UBC3, UBCH3, UBE2R1,)
• NCBI Gene ID: 997
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P49427
  UNIPROT ID#>>A0A024R1Z1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cell division cycle 34, ubiqiutin conjugating enzyme interacts with:

• 3-hydroxyacyl-CoA dehydratase 3
  7-dehydrocholesterol reductase
  acetyl-CoA acyltransferase 2
  actin related protein 2
  activating signal cointegrator 1 complex subunit 3
  activating transcription factor 5
  acyl-CoA dehydrogenase family member 11
  acyl-CoA synthetase family member 3
  acyl-CoA synthetase long chain family member 3
  ADP ribosylation factor like GTPase 6 interacting protein 5
  ADP ribosylation factor like GTPase 8A
  ADP ribosylation factor like GTPase 8B
  AFG3 like matrix AAA peptidase subunit 2
  alanyl-tRNA synthetase 2, mitochondrial
  alkylglycerone phosphate synthase
  aminopeptidase puromycin sensitive
  angiomotin
  argonaute RISC catalytic component 2
  asparaginyl-tRNA synthetase 1
  AT-hook containing transcription factor 1
  ATP binding cassette subfamily D member 3
  ATP binding cassette subfamily F member 2
  BAG cochaperone 2
  beta-transducin repeat containing E3 ubiquitin protein ligase
  cAMP responsive element modulator
  casein kinase 1 gamma 2
  casein kinase 2 beta
  catenin beta 1
  cell cycle and apoptosis regulator 2
  cell division cycle 34, ubiqiutin conjugating enzyme
  chaperonin containing TCP1 subunit 8
  chromobox 3
  chromodomain helicase DNA binding protein 4
  cleavage and polyadenylation specific factor 1
  cleavage and polyadenylation specific factor 3
  coiled-coil domain containing 47
  COPI coat complex subunit alpha
  COPI coat complex subunit beta 1
  cornulin
  coronin 7
  cullin 1
  cullin 2
  cullin 3
  cullin 5
  cyclin dependent kinase 9
  cyclin dependent kinase inhibitor 1B
  DEAD-box helicase 46
  DEAD-box helicase 47
  DExH-box helicase 57
  DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
  disco interacting protein 2 homolog B
  DnaJ heat shock protein family (Hsp40) member A1
  DnaJ heat shock protein family (Hsp40) member A2
  DnaJ heat shock protein family (Hsp40) member C10
  dynein cytoplasmic 1 heavy chain 1
  dynein cytoplasmic 1 light intermediate chain 1
  elaC ribonuclease Z 2
  elongator complex protein 1
  enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
  eukaryotic translation elongation factor 2
  eukaryotic translation initiation factor 3 subunit B
  exocyst complex component 4
  exportin 1
  exportin for tRNA
  extended synaptotagmin 1
  Fas associated factor family member 2
  FAST kinase domains 5
  fatty acid synthase
  fatty acyl-CoA reductase 1
  F-box and leucine rich repeat protein 2
  F-box and leucine rich repeat protein 3
  F-box and WD repeat domain containing 11
  F-box and WD repeat domain containing 2
  F-box and WD repeat domain containing 7
  F-box protein 32
  F-box protein 4
  F-box protein 7
  FKBP prolyl isomerase 4
  G protein nucleolar 3
  G protein subunit alpha i3
  G3BP stress granule assembly factor 1
  GCN1 activator of EIF2AK4
  gem nuclear organelle associated protein 5
  general transcription factor IIIC subunit 1
  general transcription factor IIIC subunit 3
  glucosamine-6-phosphate deaminase 1
  glucosidase II alpha subunit
  glutamic-oxaloacetic transaminase 2
  glutamyl-prolyl-tRNA synthetase 1
  glycyl-tRNA synthetase 1
  guanine monophosphate synthase
  heat shock protein 90 alpha family class A member 1
  heat shock protein 90 alpha family class B member 1
  heat shock protein family A (Hsp70) member 1A
  heat shock protein family A (Hsp70) member 1B
  heat shock protein family A (Hsp70) member 2
  heat shock protein family A (Hsp70) member 4
  heat shock protein family A (Hsp70) member 4 like
  heat shock protein family A (Hsp70) member 5
  heat shock protein family A (Hsp70) member 6
  heat shock protein family A (Hsp70) member 8
  histidine triad nucleotide binding protein 1
  histone deacetylase 1
  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
  hypoxia inducible factor 1 subunit alpha
  inhibitor of growth family member 4
  insulin receptor substrate 4
  iron-sulfur cluster assembly factor IBA57
  isoprenylcysteine carboxyl methyltransferase
  itchy E3 ubiquitin protein ligase
  karyopherin subunit alpha 1
  karyopherin subunit alpha 6
  KDEL endoplasmic reticulum protein retention receptor 1
  kelch like ECH associated protein 1
  kinesin family member C1
  La ribonucleoprotein 1, translational regulator
  lactamase beta
  lamin B receptor
  lamin B1
  LanC like 2
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat containing 47
  leucyl-tRNA synthetase 1
  leucyl-tRNA synthetase 2, mitochondrial
  LUC7 like 3 pre-mRNA splicing factor
  lysine demethylase 1A
  lysophosphatidylcholine acyltransferase 1
  matrix AAA peptidase interacting protein 1
  MDM2 proto-oncogene
  membrane associated ring-CH-type finger 1
  membrane associated ring-CH-type finger 2
  mesenchyme homeobox 1
  mesenchyme homeobox 2
  methionyl-tRNA synthetase 1
  methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
  methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
  midasin AAA ATPase 1
  minichromosome maintenance complex component 3
  minichromosome maintenance complex component 4
  minichromosome maintenance complex component 6
  minichromosome maintenance complex component 7
  mitochondrial E3 ubiquitin protein ligase 1
  mitofusin 2
  mutS homolog 6
  MYB proto-oncogene like 2
  myogenic differentiation 1
  N-acetyltransferase 10
  N-alpha-acetyltransferase 50, NatE catalytic subunit
  NEDD4 like E3 ubiquitin protein ligase
  NEDD8 ubiquitin like modifier
  NFKB inhibitor alpha
  NMD3 ribosome export adaptor
  non-SMC condensin I complex subunit D2
  NOP58 ribonucleoprotein
  NRAS proto-oncogene, GTPase
  nuclear cap binding protein subunit 1
  nucleoporin 107
  nucleoporin 155
  nucleoporin 205
  nucleoporin 93
  parkin RBR E3 ubiquitin protein ligase
  peptidylprolyl isomerase A
  peptidylprolyl isomerase F
  peptidylprolyl isomerase like 2
  peptidyl-tRNA hydrolase 2
  peroxisome proliferator activated receptor alpha
  peroxisome proliferator activated receptor gamma
  PGAM family member 5, mitochondrial serine/threonine protein phosphatase
  phosphoenolpyruvate carboxykinase 2, mitochondrial
  phosphofructokinase, platelet
  phospholipase C gamma 1
  phosphoribosyl pyrophosphate synthetase associated protein 2
  phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
  phosphoribosylformylglycinamidine synthase
  Pim-1 proto-oncogene, serine/threonine kinase
  polyribonucleotide nucleotidyltransferase 1
  potassium channel tetramerization domain containing 12
  procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
  progesterone receptor membrane component 1
  programmed cell death 6 interacting protein
  prolactin regulatory element binding
  proteasome 26S subunit, non-ATPase 2
  proteasome 26S subunit, non-ATPase 3
  protein kinase, DNA-activated, catalytic subunit
  protein phosphatase 1 catalytic subunit beta
  protein phosphatase 1 catalytic subunit gamma
  protein phosphatase 2 regulatory subunit Balpha
  protein-L-isoaspartate (D-aspartate) O-methyltransferase
  PTTG1 regulator of sister chromatid separation, securin
  pyruvate carboxylase
  pyruvate kinase M1/2
  quinoid dihydropteridine reductase
  RAB10, member RAS oncogene family
  RAB13, member RAS oncogene family
  RAB14, member RAS oncogene family
  RAB18, member RAS oncogene family
  RAB1A, member RAS oncogene family
  RAB1B, member RAS oncogene family
  RAB21, member RAS oncogene family
  RAB2B, member RAS oncogene family
  RAB3A, member RAS oncogene family
  RAB3D, member RAS oncogene family
  RAB5C, member RAS oncogene family
  RAB7A, member RAS oncogene family
  RAB8A, member RAS oncogene family
  RAB8B, member RAS oncogene family
  RAB9A, member RAS oncogene family
  Rac family small GTPase 1
  RAD21 cohesin complex component
  RAD23 homolog A, nucleotide excision repair protein
  RAD50 double strand break repair protein
  RAN binding protein 2
  Ran GTPase activating protein 1
  RAP1A, member of RAS oncogene family
  RAP1B, member of RAS oncogene family
  RAP2B, member of RAS oncogene family
  RAP2C, member of RAS oncogene family
  ras homolog family member T2
  RAS related
  recombination activating 1
  RecQ like helicase
  RecQ like helicase 4
  RELA proto-oncogene, NF-kB subunit
  Rho associated coiled-coil containing protein kinase 1
  ribonucleotide reductase catalytic subunit M1
  ribosomal protein L12
  ribosomal protein L9
  ribosomal protein S14
  ribosomal protein S17
  ribosomal RNA processing 1B
  ring finger protein 31
  ring finger protein 7
  ring-box 1
  RNA polymerase II subunit A
  RNA polymerase II subunit B
  S1 RNA binding domain 1
  SAMM50 sorting and assembly machinery component
  SEC63 homolog, protein translocation regulator
  serine/threonine kinase receptor associated protein
  siah E3 ubiquitin protein ligase 1
  signal recognition particle 14
  signal sequence receptor subunit 4
  solute carrier family 1 member 5
  solute carrier family 16 member 1
  solute carrier family 25 member 10
  solute carrier family 25 member 12
  solute carrier family 25 member 13
  solute carrier family 27 member 4
  solute carrier family 7 member 5
  S-phase kinase associated protein 2
  structural maintenance of chromosomes 1A
  structural maintenance of chromosomes 2
  structural maintenance of chromosomes 3
  structural maintenance of chromosomes 4
  structural maintenance of chromosomes 5
  STT3 oligosaccharyltransferase complex catalytic subunit A
  STT3 oligosaccharyltransferase complex catalytic subunit B
  succinate dehydrogenase complex flavoprotein subunit A
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
  syndecan binding protein
  taxilin alpha
  t-complex 1
  threonyl-tRNA synthetase 1
  threonyl-tRNA synthetase 2, mitochondrial
  trans-2,3-enoyl-CoA reductase
  transcription elongation factor A N-terminal and central domain containing 2
  transducin beta like 1 X-linked
  transducin beta like 3
  transketolase
  translocase of inner mitochondrial membrane 44
  transmembrane protein 165
  transmembrane protein 33
  tripartite motif containing 21
  tripartite motif containing 28
  tripartite motif containing 29
  tryptophanyl-tRNA synthetase 1
  Ts translation elongation factor, mitochondrial
  ubiquitin B
  ubiquitin C
  ubiquitin conjugating enzyme E2 D3
  ubiquitin like modifier activating enzyme 1
  ubiquitin specific peptidase 5
  von Hippel-Lindau tumor suppressor
  WD repeat domain 3
  WD repeat domain 6
  WD repeat domain 75
  WW domain containing E3 ubiquitin protein ligase 2
  zinc and ring finger 1
  zinc finger AN1-type containing 6
  zinc finger CCCH-type containing, antiviral 1 like

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.