AARS2, alanyl-tRNA synthetase 2, mitochondrial

AARS2, alanyl-tRNA synthetase 2, mitochondrial

• The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011]

• Gene Synonyms (AARSL, COXPD8, LKENP, MT-ALARS, MTALARS, alanine--tRNA ligase, mitochondrial, alanine tRNA ligase 2, mitochondrial (putative), alanyl-tRNA synthetase 2, mitochondrial (putative), alanyl-tRNA synthetase like, probable alanyl-tRNA synthetase, mitochondrial,)
• NCBI Gene ID: 57505
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5JTZ9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

alanyl-tRNA synthetase 2, mitochondrial interacts with:

• BCL2 like 14
  coiled-coil domain containing 8
  dehydrogenase/reductase 4 like 2
  GrpE like 1, mitochondrial
  LEO1 homolog, Paf1/RNA polymerase II complex component
  mitochondrial ribosomal protein S5
  mitochondrial rRNA methyltransferase 1
  multiple EGF like domains 10
  NADH:ubiquinone oxidoreductase core subunit S7
  oxidoreductase like domain containing 1
  pleckstrin homology domain containing A4
  zinc and ring finger 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.