LEO1, LEO1 homolog, Paf1/RNA polymerase II complex component

LEO1, LEO1 homolog, Paf1/RNA polymerase II complex component

• LEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (RDL, RNA polymerase-associated protein LEO1, Leo1 Paf1/RNA polymerase II complex component, Leo1, Paf1/RNA polymerase II complex component, homolog, replicative senescence down-regulated leo1-like protein,)
• NCBI Gene ID: 123169
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WVC0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

LEO1 homolog, Paf1/RNA polymerase II complex component interacts with:

• biorientation of chromosomes in cell division 1 like 1
  cyclin dependent kinase 11A
  family with sequence similarity 98 member B
  LEO1 homolog, Paf1/RNA polymerase II complex component
  LTO1 maturation factor of ABCE1
  mitochondrial contact site and cristae organizing system subunit 10
  mitochondrial ribosomal protein L10
  nucleoporin 43
  translocase of inner mitochondrial membrane 23 homolog B
  zinc finger CCCH-type containing 18

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.