ACSF3, acyl-CoA synthetase family member 3

ACSF3, acyl-CoA synthetase family member 3

• This gene encodes a member of the acyl-CoA synthetase family of enzymes that activate fatty acids by catalyzing the formation of a thioester linkage between fatty acids and coenzyme A. The encoded protein is localized to mitochondria, has high specificity for malonate and methylmalonate and possesses malonyl-CoA synthetase activity. Mutations in this gene are a cause of combined malonic and methylmalonic aciduria. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Sep 2013]

• Gene Synonyms (malonate--CoA ligase ACSF3, mitochondrial, acyl-CoA synthetase family member 3, mitochondrial, malonyl-CoA synthetase,)
• NCBI Gene ID: 197322
• Species: Homo sapiens (Human)
• UNIPROT ID#>>F5H5A1
  UNIPROT ID#>>Q4G176
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

acyl-CoA synthetase family member 3 interacts with:

• NADH:ubiquinone oxidoreductase core subunit S7
  oxidoreductase like domain containing 1
  transmembrane protein 184A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.