TMEM165, transmembrane protein 165

TMEM165, transmembrane protein 165

• This gene encodes a predicted transmembrane protein with a perinuclear Golgi-like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation, type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

• Gene Synonyms (CDG2K, FT27, GDT1, TMPT27, TPARL, transmembrane protein 165, TPA regulated locus, transmembrane protein PT27, transmembrane protein TPARL,)
• NCBI Gene ID: 55858
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HC07
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transmembrane protein 165 interacts with:

• cytochrome b5 type B
  egl-9 family hypoxia inducible factor 3
  kelch-like 21
  pleckstrin homology domain containing A4
  PR/SET domain 16
  protein prenyltransferase alpha subunit repeat containing 1
  SNW domain containing 1
  structural maintenance of chromosomes 6
  transmembrane protein 41B
  tubulin, gamma 1
  ubiquitin specific peptidase 43
  WD repeat domain 62

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.