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SIAH1, siah E3 ubiquitin protein ligase 1

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SIAH1, siah E3 ubiquitin protein ligase 1

  • This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]

  • Gene Synonyms (E3 ubiquitin-protein ligase SIAH1, RING-type E3 ubiquitin transferase SIAH1, seven in absentia homolog 1, siah-1a, SIAH1A,)
  • NCBI Gene ID: 6477
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q8IUQ4
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

siah E3 ubiquitin protein ligase 1 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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