USP19, ubiquitin specific peptidase 19

USP19, ubiquitin specific peptidase 19

• Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This protein is a ubiquitin protein ligase and plays a role in muscle wasting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]

• Gene Synonyms (ZMYND9, ubiquitin carboxyl-terminal hydrolase 19, deubiquitinating enzyme 19, ubiquitin specific protease 19, ubiquitin thioesterase 19, ubiquitin thiolesterase 19, ubiquitin-specific-processing protease 19, zinc finger MYND domain-containing protein 9,)
• NCBI Gene ID: 10869
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O94966
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin specific peptidase 19 interacts with:

• 5'-3' exoribonuclease 2
  ATPase family AAA domain containing 1
  calcyclin binding protein
  cell division cycle 37 like 1
  cell division cycle 37, HSP90 cochaperone
  crystallin lambda 1
  dedicator of cytokinesis 5
  dedicator of cytokinesis 7
  derlin 1
  Fas associated factor family member 2
  Fer3 like bHLH transcription factor
  FKBP prolyl isomerase 8
  FKBP prolyl isomerase like
  GCN1 activator of EIF2AK4
  kaptin, actin binding protein
  late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
  limb development membrane protein 1 like
  linker for activation of T cells
  mitochondrial antiviral signaling protein
  neuralized E3 ubiquitin protein ligase 4
  nucleoporin 160
  OTU deubiquitinase with linear linkage specificity like
  Parkinsonism associated deglycase
  pleckstrin homology domain containing A4
  RNA polymerase II associated protein 3
  SEC61 translocon subunit alpha 1
  SEC61 translocon subunit alpha 2
  serum amyloid A like 1
  small nuclear ribonucleoprotein U5 subunit 200
  SRP receptor subunit beta
  synoviolin 1
  transmembrane protein 33
  transportin 3
  unc-45 myosin chaperone A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.